Journal
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
Volume 74, Issue 11, Pages 3591-3595Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AEM.00098-08
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Coenzyme F-420-dependent sulfite reductase (Fsr) of Methanocaldococcus jannaschii, a sulfite-tolerant methanogen, was expressed with activity in Methanococcus maripaludis, a sulfite-sensitive methanogen. The recombinant organism reduced sulfite to sulfide and grew with sulfite as the sole sulfur source, indicating that Fsr is a sulfite detoxification and assimilation enzyme for methanogens and that M. maripaludis synthesizes siroheme.
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