Journal
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
Volume 75, Issue 1, Pages 281-285Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AEM.01803-08
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- U. S. Department of Agriculture, Agricultural Research Service [5325-42000-045]
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Inactivation of luxS, encoding an AI-2 biosynthesis enzyme, in Campylobacter jejuni strain 81-176 significantly reduced colonization of the chick lower gastrointestinal tract, chemotaxis toward organic acids, and in vitro adherence to LMH chicken hepatoma cells. Thus, AI-2 production in C. jejuni contributes to host colonization and interactions with epithelial cells.
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