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Mitochondrial fission in apoptosis

Journal

NATURE REVIEWS MOLECULAR CELL BIOLOGY
Volume 6, Issue 8, Pages 657-663

Publisher

NATURE PUBLISHING GROUP
DOI: 10.1038/nrm1697

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Mitochondria fuse and divide continuously within cells to form a dynamic network. One of the steps in apoptosis is the fragmentation of mitochondria, and recent evidence indicates that the mitochondrial fission machinery actively participates in the process of programmed cell death.

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