4.6 Article

Novel Cold-Adapted Alkaline Lipase from an Intertidal Flat Metagenome and Proposal for a New Family of Bacterial Lipases

Journal

APPLIED AND ENVIRONMENTAL MICROBIOLOGY
Volume 75, Issue 1, Pages 257-260

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/AEM.01400-08

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Funding

  1. 21C Frontier Program of Microbial Genomics and Applications [MG05-0401-2-0]
  2. Ministry of Education, Science and Technology (MEST) of the Republic of Korea

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A new lipase, LipEH166, isolated from an intertidal flat metagenome, showed no amino acid similarity to any known lipolytic enzyme except in the consensus region. This suggested that LipEH166 and its homologues belong to a new family of lipolytic enzymes. Partial characterization indicated that LipEH166 is a novel cold-adapted alkaline lipase.

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