Journal
METHODS
Volume 36, Issue 4, Pages 383-394Publisher
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.ymeth.2005.03.009
Keywords
mass spectrometry; electron capture dissociation; histones; posttranslational modifications; quantitation
Funding
- PHS HHS [01614] Funding Source: Medline
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The uses of tandem and Fourier transform mass spectrometric methodologies for assignment of the posttranslational sites. and occupancies of histones and their isoforms is described employing several illustrative examples. A comparison of information that can be obtained from intact protein sequencing and proteolytic digestion is presented. (c) 2005 Elsevier Inc. All rights reserved.
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