4.8 Article

Single-step synthesis of D3h-symmetric bicyclooxacalixarenes

Journal

ORGANIC LETTERS
Volume 7, Issue 16, Pages 3505-3507

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol051180q

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Bicyclooxacalixarenes are obtained in up to 95% yield by condensation of phloroglucinol with electron-poor meta-dihalogenated benzenes or pyridines. Single-crystal X-ray analysis reveals that these compounds adopt highly symmetrical, all-1,3-alternate cage-like structures.

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