☆ 4.4 Article

The Huisgen 1,4-dipolar cycloaddition involving isoquinoline, dimethyl butynedioate and activated styrenes: a facile synthesis of tetrahydrobenzoquinolizine derivatives

TETRAHEDRON LETTERS (2005)

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Journal

TETRAHEDRON LETTERS
Volume 46, Issue 32, Pages 5333-5335

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2005.06.014

Keywords

multicomponent reactions; isoquinoline; dimethyl acetylenedicarboxylate; 1,4-dipolar cycloaddition

Categories

Chemistry, Organic

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A three-component reaction involving isoquinoline, dimethyl butynedioate and electrophilic styrenes is described. The reaction proceeds through a Huisgen 1,4-dipolar cycloaddition pathway. (c) 2005 Elsevier Ltd. All rights reserved.

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