Journal
NEUROLOGY
Volume 65, Issue 3, Pages 444-447Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1212/01.WNL.0000168259.94991.8a
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Funding
- NINDS NIH HHS [NS39521] Funding Source: Medline
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This randomized, double-blind, placebo-controlled crossover study measured the effect of a single dose of oral gabapentin (900 mg) on pain and allodynia associated with herpes zoster. Pain severity decreased by 66% with gabapentin compared to 33% with placebo. Reductions in allodynia area and severity, and overall pain relief, were also greater with gabapentin.
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