4.5 Article

Discovery and in vitro evaluation of potent kinase inhibitors:: Pyrido[1',2':1,5]pyrazolo[3,4-d]pyrimidines

Journal

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 15, Issue 16, Pages 3778-3781

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2005.05.100

Keywords

kinase inhibitor; VEGFR; GSK; Erb; EGFR

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The discovery, synthesis, potential binding mode, and in vitro kinase profile of several pyrido[1',2':1,5]pyrazolo[3,4-d]pyrimidines as potent kinase inhibitors are discussed. (c) 2005 Elsevier Ltd. All rights reserved.

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