Journal
BIOINFORMATICS
Volume 21, Issue 16, Pages 3431-3432Publisher
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/bti508
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Aligning hundreds of sequences using progressive alignment tools such as ClustalW requires several hours on state-of-the-art workstations. We present a new approach to compute multiple sequence alignments in far shorter time using reconfigurable hardware. This results in an implementation of ClustalW with significant runtime savings on a standard off-the-shelf FPGA.
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