Journal
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 127, Issue 32, Pages 11348-11351Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ja051362f
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Funding
- NIBIB NIH HHS [EB-00675] Funding Source: Medline
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Molecules that perform Boolean calculations can analyze a series of inputs and make a decision to produce or not to produce an output, based on the presence or absence of inputs and a particular formula they encode. We now report that molecular computation performed by deoxyribozyme-based logic gates can be used to control the functional state of aptamers, switching them on or off based on the outcome of such computation.
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