4.8 Article

One-step assembly of functionalized γ-butyrolactones from benzoins or benzaldehydes via an N-heterocyclic carbene-mediated tandem reaction

Journal

ORGANIC LETTERS
Volume 7, Issue 17, Pages 3769-3771

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol051422m

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We describe here a direct, efficient, one-step construction of gamma,gamma-difunctionalized gamma-butyrolactones from benzoins or benzaldehydes via a tandem reaction promoted by 1,3-dimethyl imidazolin-2-ylidene, an N-heterocyclic carbene (NHC).

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