4.5 Article

Fluoroalkylation of porphyrins: A facile synthesis of trifluoromethylated porphyrins by a palladium-catalyzed cross-coupling reaction

Journal

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2005, Issue 17, Pages 3680-3686

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.200500027

Keywords

porphyrins; palladium; As ligands; fluorine

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Various trifluoromethylated porphyrins can be conveniently synthesized in high yields by the reaction of brominated porphyrins with FSO2CF2COOMe/CuI in the presence of catalytic amounts of Pd-2(dba)(3)(CHCI3)-C-./AsPh3. ((c) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005).

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