4.4 Article

Xanthomonas campestris pv. campestris possesses a single gluconeogenic pathway that is required for virulence

Journal

JOURNAL OF BACTERIOLOGY
Volume 187, Issue 17, Pages 6231-6237

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/JB.187.17.6231-6237.2005

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Disruption of ppsA, a key gene in gluconeogenesis, of Xanthomonas campestris pv. campestris resulted in the failure of the pathogen to grow in medium with pyruvate or C-4-dicarboxylates as the sole carbon source and a significant reduction in virulence, indicating that X. campestris pv. campestris possesses only the malic enzyme-PpsA route in gluconeogenesis, which is required for virulence.

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