Journal
FRONTIERS IN BIOSCIENCE-LANDMARK
Volume 10, Issue -, Pages 2750-2757Publisher
IMR PRESS
DOI: 10.2741/1732
Keywords
inflammation; thrombosis; vascular disease; inflammatory mediators; thrombogenesis; tissue factor; adhesion molecules; microparticles; review
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Vessel wall endothelial damage initiates a local inflammatory response, which promotes a prothrombotic state driven by tissue factor, adhesion molecules, and proinflammatory cytokines. Understanding how natural inflammatory mechanisms promote a procoagulant state, may lead to the development of new pharmacological interventions targeted at thrombosis.
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