Journal
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
Volume 71, Issue 9, Pages 5610-5613Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AEM.71.9.5610-5613.2005
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A four-step flavanone biosynthetic pathway was constructed and introduced into Saccharomyces cerevisiae. The recombinant yeast strain was fed with phenylpropanoid acids and produced the flavanones naringenin and pinocembrin 62 and 22 times more efficiently compared to previously reported recombinant prokaryotic strains. Microbial biosynthesis of the flavanone eriodictyol was also achieved.
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