4.8 Article

A novel palladium-catalyzed arylation-dehydroaromatization reaction: Synthesis of 7-aryltetralones

Journal

ORGANIC LETTERS
Volume 7, Issue 18, Pages 3881-3884

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol051290x

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A new one-pot room-temperature palladium-catalyzed synthesis of 7-aryltetralones was discovered. This tandem process includes a palladium-catalyzed gamma-selective arylation of the enone 4 followed by a dehydrogenation-aromatization of the initial cross-coupling product.

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