Journal
ORGANIC LETTERS
Volume 7, Issue 19, Pages 4257-4260Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol0516871
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Condensation of squaric acid with a number of differently substituted 2-pyrrolyl derivatives afforded three new classes of squaraines. Their sharp and intense absorption bands in the biological window (700-900 nm), inherent singlet oxygen generation capabilities, together with proper functionalization allowing good water solubility make them suitable candidates as new non-porphyrinic singlet oxygen photosensitizers for photodynamic therapy (PDT).
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