Journal
ORGANIC LETTERS
Volume 7, Issue 19, Pages 4083-4086Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol051200o
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The key fragment (2a or 2b) in a total synthesis of the cytotoxic macrolide (-)-amphidinolide K (1) has been achieved from synthons U-CA (3) and C15-C22 (4), which have both been prepared from glutamic acid in good overall yields.
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