4.4 Article

Syntheses of vinylindoles via a Bronsted acid catalyzed highly regio- and stereoselective cis-hydroarylation of ynamides

Journal

TETRAHEDRON LETTERS
Volume 46, Issue 38, Pages 6483-6486

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2005.07.098

Keywords

ynamides; vinylindole; hydroarylation

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A highly regio- and stereoselective Bronsted acid-catalyzed coupling of ynamides and indoles is described. This process is the equivalent of hydroarylation of ynamides and leads to the efficient syntheses of vinylindoles. Diels-Alder reaction between the vinylindoles and DMAD afforded carbazole derivatives in good yields. (c) 2005 Elsevier Ltd. All rights reserved.

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