Journal
ORGANIC LETTERS
Volume 7, Issue 20, Pages 4349-4352Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol0514698
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graph 5 '-Peptide oligonucleotide conjugates were prepared stepwise on a single support using W-Fmoc-protected amino acids and unprotected phosphate groups. The method uses commercially available reagents and is successful with most natural amino acids. The simplicity of the method may encourage researchers to prepare new oligonucleotide-peptide conjugates with novel properties.
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