4.8 Article

Di-tert-butylsilylene-directed α-selective synthesis of 4-methylumbelliferyl T-antigen

Journal

ORGANIC LETTERS
Volume 7, Issue 20, Pages 4415-4418

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol051592z

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We have succeeded in the facile synthesis of 4-methylumbelliferyl T-antigen as a substrate for endo-alpha-N-acetylgalactosaminidase by exploiting the combination of the di-tert-butylsilylene effect and the Mitsunobu reaction.

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