Related references
Note: Only part of the references are listed.Heterologous expression of natural product biosynthetic gene clusters in Streptomyces coelicolor: from genome mining to manipulation of biosynthetic pathways
Juan Pablo Gomez-Escribano et al.
JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY (2014)
An environmental bacterial taxon with a large and distinct metabolic repertoire
Micheal C. Wilson et al.
NATURE (2014)
Diversity and evolution of secondary metabolism in the marine actinomycete genus Salinispora
Nadine Ziemert et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Metagenomic Approaches for Exploiting Uncultivated Bacteria as a Resource for Novel Biosynthetic Enzymology
Micheal C. Wilson et al.
CHEMISTRY & BIOLOGY (2013)
Meta-omic characterization of prokaryotic gene clusters for natural product biosynthesis
Michael M. Schofield et al.
CURRENT OPINION IN BIOTECHNOLOGY (2013)
Coprophilous fungi: antibiotic discovery and functions in an underexplored arena of microbial defensive mutualism
Gerald F. Bills et al.
CURRENT OPINION IN MICROBIOLOGY (2013)
Developing new antibacterials through natural product research
Herbert A. Kirst
EXPERT OPINION ON DRUG DISCOVERY (2013)
Engineering fungal secondary metabolism: A roadmap to novel compounds
Daniel H. Scharf et al.
JOURNAL OF BIOTECHNOLOGY (2013)
Platforms for antibiotic discovery
Kim Lewis
NATURE REVIEWS DRUG DISCOVERY (2013)
Engineered Streptomyces avermitilis Host for Heterologous Expression of Biosynthetic Gene Cluster for Secondary Metabolites
Mamoru Komatsu et al.
ACS SYNTHETIC BIOLOGY (2013)
Chemical and Physical Modulation of Antibiotic Activity in Emericella Species
Mercedes de la Cruz et al.
CHEMISTRY & BIODIVERSITY (2012)
Antibiotics: A New Hope
Gerard D. Wright
CHEMISTRY & BIOLOGY (2012)
Chemical Perturbation of Secondary Metabolism Demonstrates Important Links to Primary Metabolism
Arryn Craney et al.
CHEMISTRY & BIOLOGY (2012)
Fidaxomicin: A Novel Macrocyclic Antibiotic Approved for Treatment of Clostridium difficile Infection
Anilrudh A. Venugopal et al.
CLINICAL INFECTIOUS DISEASES (2012)
Synthetic biological approaches to natural product biosynthesis
Jaclyn M. Winter et al.
CURRENT OPINION IN BIOTECHNOLOGY (2012)
Improving known classes of antibiotics: an optimistic approach for the future
Karen Bush
CURRENT OPINION IN PHARMACOLOGY (2012)
Recent derivatives from smaller classes of fermentation-derived antibacterials
Herbert A. Kirst
EXPERT OPINION ON THERAPEUTIC PATENTS (2012)
Metabolomics methods for the synthetic biology of secondary metabolism
Quoc-Thai Nguyen et al.
FEBS LETTERS (2012)
Thoughts and facts about antibiotics: Where we are now and where we are heading
Janos Berdy
JOURNAL OF ANTIBIOTICS (2012)
Marine actinomycetes as an emerging resource for the drug development pipelines
Sergey B. Zotchev
JOURNAL OF BIOTECHNOLOGY (2012)
Natural Products As Sources of New Drugs over the 30 Years from 1981 to 2010
David J. Newman et al.
JOURNAL OF NATURAL PRODUCTS (2012)
Metagenome Mining Reveals Polytheonamides as Posttranslationally Modified Ribosomal Peptides
Michael F. Freeman et al.
SCIENCE (2012)
Approaches to Capturing and Designing Biologically Active Small Molecules Produced by Uncultured Microbes
Joern Piel
ANNUAL REVIEW OF MICROBIOLOGY, VOL 65 (2011)
Mycolic Acid-Containing Bacteria Induce Natural-Product Biosynthesis in Streptomyces Species
Hiroyasu Onaka et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2011)
Bacterial symbionts and natural products
Jason M. Crawford et al.
CHEMICAL COMMUNICATIONS (2011)
Discovery of Kibdelomycin, A Potent New Class of Bacterial Type II Topoisomerase Inhibitor by Chemical-Genetic Profiling in Staphylococcus aureus
John W. Phillips et al.
CHEMISTRY & BIOLOGY (2011)
Challenges of Antibacterial Discovery
Lynn L. Silver
CLINICAL MICROBIOLOGY REVIEWS (2011)
Genomics-inspired discovery of natural products
Jaclyn M. Winter et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2011)
Natural products as catalysts for innovation: a pharmaceutical industry perspective
Esther K. Schmitt et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2011)
Screening strategies for discovery of antibacterial natural products
Sheo B. Singh et al.
EXPERT REVIEW OF ANTI-INFECTIVE THERAPY (2011)
Fungal secondary metabolites - Strategies to activate silent gene clusters
Axel A. Brakhage et al.
FUNGAL GENETICS AND BIOLOGY (2011)
Antibiotics in the clinical pipeline in 2011
Mark S. Butler et al.
JOURNAL OF ANTIBIOTICS (2011)
Current approaches to exploit actinomycetes as a source of novel natural products
Olga Genilloud et al.
JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY (2011)
The regulation of the secondary metabolism of Streptomyces: new links and experimental advances
Gilles P. van Wezel et al.
NATURAL PRODUCT REPORTS (2011)
A mass spectrometry-guided genome mining approach for natural product peptidogenomics
Roland D. Kersten et al.
NATURE CHEMICAL BIOLOGY (2011)
antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences
Marnix H. Medema et al.
NUCLEIC ACIDS RESEARCH (2011)
Structure elucidation and biosynthesis of lysine-rich cyclic peptides in Xenorhabdus nematophila
Sebastian W. Fuchs et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2011)
Identification of a bioactive 51-membered macrolide complex by activation of a silent polyketide synthase in Streptomyces ambofaciens
Luisa Laureti et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Avenolide, a Streptomyces hormone controlling antibiotic production in Streptomyces avermitilis
Shigeru Kitani et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Myxococcus xanthus induces actinorhodin overproduction and aerial mycelium formation by Streptomyces coelicolor
Juana Perez et al.
MICROBIAL BIOTECHNOLOGY (2011)
Capturing Bacterial Metabolic Exchange Using Thin Film Desorption Electrospray Ionization-Imaging Mass Spectrometry
Jeramie Watrous et al.
ANALYTICAL CHEMISTRY (2010)
Closthioamide: An Unprecedented Polythioamide Antibiotic from the Strictly Anaerobic Bacterium Clostridium cellulolyticum
Thorger Lincke et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2010)
Production of microbial secondary metabolites: Regulation by the carbon source
Beatriz Ruiz et al.
CRITICAL REVIEWS IN MICROBIOLOGY (2010)
Recent application of metagenomic approaches toward the discovery of antimicrobials and other bioactive small molecules
Jacob J. Banik et al.
CURRENT OPINION IN MICROBIOLOGY (2010)
SMURF: Genomic mapping of fungal secondary metabolite clusters
Nora Khaldi et al.
FUNGAL GENETICS AND BIOLOGY (2010)
Coelomycin, a highly substituted 2,6-dioxo-pyrazine fungal metabolite antibacterial agent discovered by Staphylococcus aureus fitness test profiling
Michael A. Goetz et al.
JOURNAL OF ANTIBIOTICS (2010)
Uncultured microorganisms as a source of secondary metabolites
Kim Lewis et al.
JOURNAL OF ANTIBIOTICS (2010)
Antibiotic discovery in the twenty-first century: current trends and future perspectives
Stefano Donadio et al.
JOURNAL OF ANTIBIOTICS (2010)
Induction of antimicrobial activities in heterologous streptomycetes using alleles of the Streptomyces coelicolor gene absA1
Nancy L. McKenzie et al.
JOURNAL OF ANTIBIOTICS (2010)
Natural Products Version 2.0: Connecting Genes to Molecules
Christopher T. Walsh et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)
Isolation, structure and antibacterial activity of pleosporone from a pleosporalean ascomycete discovered by using antisense strategy
Chaowei Zhang et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2009)
Strategies for the Discovery of New Natural Products by Genome Mining
Malek Zerikly et al.
CHEMBIOCHEM (2009)
A Staphylococcus aureus Fitness Test Platform for Mechanism-Based Profiling of Antibacterial Compounds
Robert G. K. Donald et al.
CHEMISTRY & BIOLOGY (2009)
Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America
Helen W. Boucher et al.
CLINICAL INFECTIOUS DISEASES (2009)
Entomopathogenic bacteria as a source of secondary metabolites
Helge B. Bode
CURRENT OPINION IN CHEMICAL BIOLOGY (2009)
Has the era of untreatable infections arrived?
David M. Livermore
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2009)
Novel Chemical Space Exploration via Natural Products
Josefin Rosen et al.
JOURNAL OF MEDICINAL CHEMISTRY (2009)
Antisense-Guided Isolation and Structure Elucidation of Pannomycin, a Substituted cis-Decalin from Geomyces pannorum
Craig A. Parish et al.
JOURNAL OF NATURAL PRODUCTS (2009)
The role of absC, a novel regulatory gene for secondary metabolism, in zinc-dependent antibiotic production in Streptomyces coelicolor A3(2)
Andy Hesketh et al.
MOLECULAR MICROBIOLOGY (2009)
Imaging mass spectrometry of natural products
Eduardo Esquenazi et al.
NATURAL PRODUCT REPORTS (2009)
Mining cyanobacterial genomes for genes encoding complex biosynthetic pathways
John A. Kalaitzis et al.
NATURAL PRODUCT REPORTS (2009)
Genomic basis for natural product biosynthetic diversity in the actinomycetes
Markus Nett et al.
NATURAL PRODUCT REPORTS (2009)
The impact of genomics on the exploitation of the myxobacterial secondary metabolome
Silke C. Wenzel et al.
NATURAL PRODUCT REPORTS (2009)
New natural product biosynthetic chemistry discovered by genome mining
Christophe Corre et al.
NATURAL PRODUCT REPORTS (2009)
Genomics of secondary metabolite production by Pseudomonas spp
Harald Gross et al.
NATURAL PRODUCT REPORTS (2009)
Antibacterial discovery in actinomycetes strains with mutations in RNA polymerase or ribosomal protein S12
Takeshi Hosaka et al.
NATURE BIOTECHNOLOGY (2009)
Telavancin
G. Ralph Corey et al.
NATURE REVIEWS DRUG DISCOVERY (2009)
A chemical epigenetics approach for engineering the in situ biosynthesis of a cryptic natural product from Aspergillus niger
Jon C. Henrikson et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2009)
Triggering cryptic natural product biosynthesis in microorganisms
Kirstin Scherlach et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2009)
Intimate bacterial-fungal interaction triggers biosynthesis of archetypal polyketides in Aspergillus nidulans
Volker Schroeckh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Antibiotics for Emerging Pathogens
Michael A. Fischbach et al.
SCIENCE (2009)
The impact of natural products upon modern drug discovery
A. Ganesan
CURRENT OPINION IN CHEMICAL BIOLOGY (2008)
Feast or famine:: the global regulator DasR links nutrient stress to antibiotic production by Streptomyces
Sebastien Rigali et al.
EMBO REPORTS (2008)
Enhancement of antibiotic and secondary metabolite detection from filamentous fungi by growth on nutritional arrays
G. F. Bills et al.
JOURNAL OF APPLIED MICROBIOLOGY (2008)
Isolation, structure, and antibacterial activity of phaeosphenone from a Phaeosphaeria sp discovered by antisense strategy
Chaowei Zhang et al.
JOURNAL OF NATURAL PRODUCTS (2008)
Mining microbial genomes for new natural products and biosynthetic pathways
Gregory L. Challis
MICROBIOLOGY-SGM (2008)
Epigenetic remodeling of the fungal secondary metabolome
Russell B. Williams et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2008)
2-Alkyl-4-hydroxymethylfuran-3-carboxylic acids, antibiotic production inducers discovered by Streptomyces coelicolor genome mining
Christophe Corre et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
The rare earth, scandium, causes antibiotic overproduction in Streptomyces spp.
Keiichi Kawai et al.
FEMS MICROBIOLOGY LETTERS (2007)
Histone deacetylase activity regulates chemical diversity in Aspergillus
E. Keats Shwab et al.
EUKARYOTIC CELL (2007)
Evolution of γ-butyrolactone synthases and receptors in Streptomyces
Hiromi Nishida et al.
ENVIRONMENTAL MICROBIOLOGY (2007)
Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties
Jun Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Species-specific secondary metabolite production in marine actinomycetes of the genus Salinispora
Paul R. Jensen et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2007)
Induced production of emericellamides A and B from the marine-derived fungus Emericella sp in competing co-culture
Dong-Chan Oh et al.
JOURNAL OF NATURAL PRODUCTS (2007)
Coniothyrione, a chlorocyclopentandienylbenzopyrone as a bacterial protein synthesis inhibitor discovered by antisense technology
John G. Ondeyka et al.
JOURNAL OF NATURAL PRODUCTS (2007)
The genomisotopic approach: A systematic method to isolate products of orphan biosynthetic gene clusters
Harald Gross et al.
CHEMISTRY & BIOLOGY (2007)
Drugs for bad bugs: confronting the challenges of antibacterial discovery
David J. Payne et al.
NATURE REVIEWS DRUG DISCOVERY (2007)
Pyocyanin isolated from a marine microbial population: Synergistic production between two distinct bacterial species and mode of action
Scott Angell et al.
CHEMISTRY & BIOLOGY (2006)
Discovery of lucensimycins A and B from streptomyces lucensis MA7349 using an antisense strategy
Sheo B. Singh et al.
ORGANIC LETTERS (2006)
Secondary metabolic gene cluster silencing in Aspergillus nidulans
Jin Woo Bok et al.
MOLECULAR MICROBIOLOGY (2006)
Platensimycin is a selective FabF inhibitor with potent antibiotic properties
J Wang et al.
NATURE (2006)
Natural products - The future scaffolds for novel antibiotics?
MS Butler et al.
BIOCHEMICAL PHARMACOLOGY (2006)
Desferrioxamine E produced by Streptomyces griseus stimulates growth and development of Streptomyces tanashiensis
K Yamanaka et al.
MICROBIOLOGY-SGM (2005)
The evolving role of natural products in drug discovery
FE Koehn et al.
NATURE REVIEWS DRUG DISCOVERY (2005)
The role of natural product chemistry in drug discovery
MS Butler
JOURNAL OF NATURAL PRODUCTS (2004)
Metabolites from symbiotic bacteria
J Piel
NATURAL PRODUCT REPORTS (2004)
The uncultured microbial majority
MS Rappe et al.
ANNUAL REVIEW OF MICROBIOLOGY (2003)
Isolating uncultivable microorganisms in pure culture in a simulated natural environment
T Kaeberlein et al.
SCIENCE (2002)
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)
SD Bentley et al.
NATURE (2002)
Pestalone, a new antibiotic produced by a marine fungus in response to bacterial challenge
M Cueto et al.
JOURNAL OF NATURAL PRODUCTS (2001)
Iron and metal regulation in bacteria
K Hantke
CURRENT OPINION IN MICROBIOLOGY (2001)
Wide distribution of interspecific stimulatory events on antibiotic production and sporulation among Streptomyces species
K Ueda et al.
JOURNAL OF ANTIBIOTICS (2000)
Share Paper
