Accumulation and depuration of paralytic shellfish poisoning toxins by laboratory cultured purple clam Hiatula diphos Linnaeus

Purple clams (Hiatula diphos Linnaeus) accumulate paralytic shellfish poisoning (PSP) toxins produced by a toxic strain of the dinoflagellate Alexandrium, minutum Halim in a laboratory study. The maximal toxicity of PSP toxins attained 31.3 MU/g after 20 days exposure. The toxin profile of H. diphos was similar to that reported for A. minutum at the end of the exposure period; and GTX1 was dominant. GTX congeners were found in muscle on day 16 and day 20, these substances could be detected during the depuration period as well. GTX1 was detected in the siphon only on day 32. The results show that H. diphos accumulates PSP toxins according to the amount and toxin profile of ingested A. minutum. (c) 2005 Elsevier Ltd. All rights reserved.