Correlation of the solubility behavior of crystalline 1-nitronapthalene in organic solvents with the Abraham solvation parameter model

The Abraham solvation parameter model is used to calculate the numerical values of the solute descriptors for 1-nitronaphthalene from experimental solubilities in organic solvents. The mathematical correlations take the form of log(10)(C-S/C-W) = c + eE + sS + aA + bB + vV log(10)(C-S/C-G) = c + eE + sS + aA + bB + lL where C-S and C-W refer to the solute solubility (molarity) in the organic solvent and water, respectively, C-G is the solute gas phase concentration, E is the solute excess molar refraction, V is the McGowan volume of the solute, A and B are measures of the solute hydrogen-bond acidity and hydrogen-bond basicity, S denotes the solute dipolarity/polarizability descriptor, and L is the logarithm of the solute gas phase dimensionless Ostwald partition coefficient into hexadecane at 298 K. The remaining symbols in the above expressions are known solvent coefficients, which have been determined previously for a large number of gas/solvent and water/solvent systems. The Abraham solvation parameter model was found to describe the experimental solubility data of 1-nitronaphthalene to within an overall standard deviation of 0.099 log units.