Biodistribution of chitosan-based magnetite suspensions for targeted hyperthermia in ICR mice

Magnetite and the chitosan-based magnetite suspensions were synthesized by spray-coprecipitation. In the 2 wt% chitosan-based magnetite suspension, the zeta-potential value was lower value at 5.6 mV relative to other concentrations of magnetic suspension. The chitosan-based magnetic suspension with a zeta potential close to zero showed increased circulation time in biodistribution of Institute of Cancer Research mice.