Journal
INFECTION AND IMMUNITY
Volume 73, Issue 10, Pages 7027-7031Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/IAI.73.10.7027-7031.2005
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Plasmid vectors and fluorescent protein reporter systems are commonly used in the study of bacterial pathogenesis. Here we show that they can impair the ability of Salmonella enterica serovar Typhimurium to productively infect either cultured mammalian cells or mice. This has significant implications for studies that rely on these systems.
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