Journal
ANTIVIRAL RESEARCH
Volume 79, Issue 1, Pages 1-5Publisher
ELSEVIER
DOI: 10.1016/j.antiviral.2008.02.002
Keywords
viral infection; molecular diagnosis; pathogen discovery; polymerase chain reaction (PCR); DNA microarray; high-throughput sequencing
Categories
Funding
- NHLBI NIH HHS [R01 HL083850, HL 83850] Funding Source: Medline
- NIAID NIH HHS [U54 AI057158, U54 AI 5758, AI 070411, U01 AI070411] Funding Source: Medline
- NINDS NIH HHS [U01 NS047537, NS 047537] Funding Source: Medline
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With globalization of microbial threats and an increasing appreciation for the role of infection in chronic as well as acute diseases, there is burgeoning interest in the development of specific antiviral drugs. Less attention has been focused on the establishment and implementation of rapid viral diagnostic methods, without which it will not be possible to obtain the full benefit of new therapies. Here we review the current status of viral diagnostics and the utility of various sequence-based diagnostic platforms for applications in clinical Microbiology, surveillance and pathogen discovery. (c) 2008 Elsevier B.V. All rights reserved.
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