4.7 Review

Role of Vitamin C in the Function of the Vascular Endothelium

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Ascorbate stimulates endothelial nitric oxide synthase enzyme activity by rapid modulation of its phosphorylation status

Angela Ladurner et al.

FREE RADICAL BIOLOGY AND MEDICINE (2012)

Review Peripheral Vascular Disease

There's More to Flow-Mediated Dilation Than Nitric Oxide

Lee Stoner et al.

JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS (2012)

Article Urology & Nephrology

Association between vitamin C deficiency and dialysis modalities

Kunying Zhang et al.

NEPHROLOGY (2012)

Article Biochemistry & Molecular Biology

Nitric oxide mediates tightening of the endothelial barrier by ascorbic acid

James M. May et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)

Article Biochemistry & Molecular Biology

Selective macrophage ascorbate deficiency suppresses early atherosclerosis

Vladimir R. Babaev et al.

FREE RADICAL BIOLOGY AND MEDICINE (2011)

Correction Cardiac & Cardiovascular Systems

Ratio of 5,6,7,8- tetrahydrobiopterin to 7,8- dihydrobiopterin in endothelial cells determines glucose- elicited changes in NO vs. superoxide production by eNOS (vol 294, H1530, 2008)

M. J. Crabtree et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2010)

Article Cell & Tissue Engineering

Vitamin C Enhances the Generation of Mouse and Human Induced Pluripotent Stem Cells

Miguel Angel Esteban et al.

CELL STEM CELL (2010)

Article Biochemistry & Molecular Biology

Ascorbate protects endothelial barrier function during septic insult: Role of protein phosphatase type 2A

Min Han et al.

FREE RADICAL BIOLOGY AND MEDICINE (2010)

Article Biochemistry & Molecular Biology

Ascorbic acid prevents increased endothelial permeability caused by oxidized low density lipoprotein

James M. May et al.

FREE RADICAL RESEARCH (2010)

Article Cell Biology

Oxidized LDL up-regulates the ascorbic acid transporter SVCT2 in endothelial cells

James M. May et al.

MOLECULAR AND CELLULAR BIOCHEMISTRY (2010)

Article Biochemistry & Molecular Biology

Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases

John R. Horton et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2010)

Article Cell & Tissue Engineering

Ascorbate Promotes Epigenetic Activation of CD30 in Human Embryonic Stem Cells

Tung-Liang Chung et al.

STEM CELLS (2010)

Article Cell & Tissue Engineering

Ascorbate inhibition of angiogenesis in aortic rings ex vivo and subcutaneous Matrigel plugs in vivo

Nina A. Mikirova et al.

VASCULAR CELL (2010)

Article Public, Environmental & Occupational Health

Vitamin C Deficiency in a Population of Young Canadian Adults

Leah Cahill et al.

AMERICAN JOURNAL OF EPIDEMIOLOGY (2009)

Article Cell Biology

Transfer of ascorbic acid across the vascular endothelium: mechanism and self-regulation

James M. May et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2009)

Article Biochemistry & Molecular Biology

Efficient repair of protein radicals by ascorbate

Anastasia S. Domazou et al.

FREE RADICAL BIOLOGY AND MEDICINE (2009)

Article Medicine, General & Internal

Antioxidant Supplements and Cardiovascular Disease in Men

Sebastian J. Padayatty

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2009)

Letter Medicine, General & Internal

Antioxidant Supplements and Cardiovascular Disease in Men

Francesco Violi et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2009)

Article Cell Biology

Ascorbic acid efflux and re-uptake in endothelial cells: maintenance of intracellular ascorbate

James M. May et al.

MOLECULAR AND CELLULAR BIOCHEMISTRY (2009)

Review Biochemistry & Molecular Biology

AMP-activated protein kinase in skeletal muscle: From structure and localization to its role as a master regulator of cellular metabolism

C. A. Witczak et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2008)

Article Pharmacology & Pharmacy

Plasma antioxidant status in septic critically ill patients: a decrease over time

Jean-Marc Doise et al.

FUNDAMENTAL & CLINICAL PHARMACOLOGY (2008)

Article Medicine, General & Internal

Vitamins E and C in the Prevention of Cardiovascular Disease in Men The Physicians' Health Study II Randomized Controlled Trial

Howard D. Sesso et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2008)

Review Pharmacology & Pharmacy

Inflammation in the vascular bed: Importance of vitamin C

Rene Aguirre et al.

PHARMACOLOGY & THERAPEUTICS (2008)

Article Cardiac & Cardiovascular Systems

Ratio of 5,6,7,8-tetrahydrobiopterin to 7,8-dihydrobiopterin in endothelial cells determines glucose-elicited changes in NO vs. superoxide production by eNOS

Mark J. Crabtree et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2008)

Article Cell Biology

α-lipoic acid and ascorbate prevent LDL oxidation and oxidant stress in endothelial cells

Anup K. Sabharwal et al.

MOLECULAR AND CELLULAR BIOCHEMISTRY (2008)

Review Biochemistry & Molecular Biology

Reactive oxygen species and cellular oxygen sensing

Timothy P. Cash et al.

FREE RADICAL BIOLOGY AND MEDICINE (2007)

Article Biochemistry & Molecular Biology

Maturational loss of the vitamin C transporter in erythrocytes

James M. May et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)

Article Biochemistry & Molecular Biology

Opposite effects of high glucose on MMP-2 and TIMP-2 in human endothelial cells

Feng M. Ho et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2007)

Article Biochemistry & Molecular Biology

Modulation of hypoxia-inducible factor-1 alpha in cultured primary cells by intracellular ascorbate

Margret C. M. Vissers et al.

FREE RADICAL BIOLOGY AND MEDICINE (2007)

Review Cardiac & Cardiovascular Systems

Regulation of endothelial and myocardial NO synthesis by multi-site eNOS phosphorylation

Peter F. Mount et al.

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2007)

Letter Medicine, Research & Experimental

Ascorbic acid as a sensor of oxidative stress and a regulator of gene expression: The Yin and Yang of vitamin C

Antonella Grano et al.

MEDICAL HYPOTHESES (2007)

Article Biochemistry & Molecular Biology

Ascorbate inhibits NADPH oxidase subunit p47phox expression in microvascular endothelial cells

Feng Wu et al.

FREE RADICAL BIOLOGY AND MEDICINE (2007)

Article Multidisciplinary Sciences

Histone demethylation by a family of JmjC domain-containing proteins

Y Tsukada et al.

NATURE (2006)

Article Biochemistry & Molecular Biology

Faster plasma vitamin E disappearance in smokers is normalized by vitamin C supplementation

RS Bruno et al.

FREE RADICAL BIOLOGY AND MEDICINE (2006)

Article Pharmacology & Pharmacy

Ca2+-mediated ascorbate release from coronary artery endothelial cells

KA Davis et al.

BRITISH JOURNAL OF PHARMACOLOGY (2006)

Article Physiology

Constitutive eNOS-derived nitric oxide is a determinant of endothelial junctional integrity

D Predescu et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2005)

Article Biochemistry & Molecular Biology

Polarized localization of vitamin C transporters, SVCT1 and SVCT2, in epithelial cells

JC Boyer et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)

Article Cell Biology

Ascorbate uptake in pig coronary artery endothelial cells

KA Best et al.

MOLECULAR AND CELLULAR BIOCHEMISTRY (2005)

Article Biochemistry & Molecular Biology

Transport and intracellular accumulation of vitamin C in endothelial cells: relevance to collagen synthesis

JM May et al.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2005)

Article Nutrition & Dietetics

Concentrations of ascorbic acid in the plasma of pregnant smokers and nonsmokers and their newborns

AM de Oliveira et al.

INTERNATIONAL JOURNAL FOR VITAMIN AND NUTRITION RESEARCH (2004)

Article Medicine, Research & Experimental

Ascorbic acid blocks the growth inhibitory effect of tumor necrosis factor-α on endothelial cells

RW Saeed et al.

EXPERIMENTAL BIOLOGY AND MEDICINE (2003)

Article Biochemistry & Molecular Biology

Recycling of vitamin C by a bystander effect

FJ Nualart et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Biophysics

Paracellular ion channel at the tight junction

VW Tang et al.

BIOPHYSICAL JOURNAL (2003)

Article Biochemistry & Molecular Biology

Ascorbic acid blunts oxidant stress due to menadione in endothelial cells

JM May et al.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2003)

Article Surgery

Ascorbic acid dynamics in the seriously ill and injured

CL Long et al.

JOURNAL OF SURGICAL RESEARCH (2003)

Article Biochemistry & Molecular Biology

Decreased plasma and cerebrospinal fluid ascorbate levels in patients with septic encephalopathy

K Voigt et al.

FREE RADICAL RESEARCH (2002)

Article Biochemistry & Molecular Biology

Oxidation of tetrahydrobiopterin by biological radicals and scavenging of the trihydrobiopterin radical by ascorbate

KB Patel et al.

FREE RADICAL BIOLOGY AND MEDICINE (2002)

Review Biochemistry & Molecular Biology

Ascorbic acid: much more than just an antioxidant

O Arrigoni et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2002)

Review Oncology

Hypoxia - A key regulatory factor in tumour growth

AL Harris

NATURE REVIEWS CANCER (2002)

Article Medicine, General & Internal

Malnutrition and mortality in Kohistan dstrict, Afghanistan, April 2001

F Assefa et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2001)

Article Multidisciplinary Sciences

A conserved family of prolyl-4-hydroxylases that modify HIF

RK Bruick et al.

SCIENCE (2001)

Article Cardiac & Cardiovascular Systems

Vitamin C inhibits endothelial cell apoptosis in congestive heart failure

L Rössig et al.

CIRCULATION (2001)

Article Biochemistry & Molecular Biology

Reaction of tetrahydrobiopterin with superoxide:: EPR-kinetic analysis and characterization of the pteridine radical

J Vásquez-Vivar et al.

FREE RADICAL BIOLOGY AND MEDICINE (2001)

Article Biochemistry & Molecular Biology

Mechanisms of ascorbic acid recycling in human erythrocytes

JM May et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2001)

Article Pharmacology & Pharmacy

Requirement for GSH in recycling of ascorbic acid in endothelial cells

JM May et al.

BIOCHEMICAL PHARMACOLOGY (2001)

Article Cardiac & Cardiovascular Systems

Effect of ascorbic acid treatment on conduit vessel endothelial dysfunction in patients with hypertension

SJ Duffy et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2001)

Article Biochemistry & Molecular Biology

L-ascorbic acid potentiates endothelial nitric oxide synthesis via a chemical stabilization of tetrahydrobiopterin

R Heller et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)

Article Biochemical Research Methods

Characterization of dehydroascorbic acid solutions by liquid chromatography/mass spectrometry

P Pastore et al.

RAPID COMMUNICATIONS IN MASS SPECTROMETRY (2001)

Article Cardiac & Cardiovascular Systems

Coronary heart disease in smokers -: Vitamin C restores coronary microcirculatory function

PA Kaufmann et al.

CIRCULATION (2000)

Article Biochemistry & Molecular Biology

Hemiketal formation of dehydroascorbic acid drives ascorbyl radical anion disproportionation

GA DiLabio et al.

FREE RADICAL BIOLOGY AND MEDICINE (2000)

Article Biochemistry & Molecular Biology

Interaction of peroxynitrite with selenoproteins and glutathione peroxidase mimics

H Sies et al.

FREE RADICAL BIOLOGY AND MEDICINE (2000)

Article Biochemistry & Molecular Biology

Reaction of uric acid with peroxynitrite and implications for the mechanism of neuroprotection by uric acid

GL Squadrito et al.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2000)

Review Biochemistry & Molecular Biology

How does ascorbic acid prevent endothelial dysfunction?

JM May

FREE RADICAL BIOLOGY AND MEDICINE (2000)