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SCIENCE (2008)
Thioredoxin-interacting protein (Txnip) is a critical regulator of hepatic glucose production
William A. Chutkow et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Suppression of Choroidal Neovascularization by Thioredoxin-1 via Interaction with Complement Factor H
Yasuya Inomata et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2008)
Runx proteins are involved in regulation of CD122, Ly49 family and IFN-gamma expression during NK cell differentiation
Shin-ichiro Ohno et al.
INTERNATIONAL IMMUNOLOGY (2008)
S-nitrosylation of peroxiredoxin 2 promotes oxidative stress-induced neuronal cell death in Parkinson's disease
Jianguo Fang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Nuclear redox-signaling is essential for apoptosis inhibition in endothelial cells - Important role for nuclear thioredoxin-1
Peter Schroeder et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2007)
Reactive aldehyde modification of thioredoxin-1 activates early steps of inflammation and cell adhesion
Young-Mi Go et al.
AMERICAN JOURNAL OF PATHOLOGY (2007)
Vascular adhesion molecules in atherosclerosis
Elena Galkina et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2007)
Targeting Thioredoxin Reductase 1 Reduction in Cancer Cells Inhibits Self-Sufficient Growth and DNA Replication
Min-Hyuk Yoo et al.
PLOS ONE (2007)
The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor
Eric L. Greer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Thioredoxin and thioredoxin-binding protein-2 in cancer and metabolic syndrome
Ahsan M. Kaimul et al.
FREE RADICAL BIOLOGY AND MEDICINE (2007)
Lipid raft-mediated uptake of cysteine-modified thioredoxin-1: Apoptosis enhancement by inhibiting the endogenous thioredoxin-1
Norihiko Kondo et al.
ANTIOXIDANTS & REDOX SIGNALING (2007)
Effects of thioredoxin on established airway remodeling in a chronic antigen exposure asthma model
Haruki Imaoka et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Inhibition of thioredoxin reductase induces apoptosis in neuronal cell lines:: Role of glutathione and the MKK4/JNK pathway
Jan Seyfried et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Thioredoxin signaling as a target for cancer therapy
Garth Powis et al.
CURRENT OPINION IN PHARMACOLOGY (2007)
Expression and extracellular release of Trx80, the truncated form of thioredoxin, by TNF-α- and IL-1β-stimulated human synoviocytes from patients with rheumatoid arthritis
Herve Lemarechal et al.
CLINICAL SCIENCE (2007)
Targeting thioredoxin reductase is a basis for cancer therapy by arsenic trioxide
Jun Lu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Thioredoxin catalyzes the denitrosation of low-molecular mass and protein S-nitrosothiols
Rajib Sengupta et al.
BIOCHEMISTRY (2007)
Thioredoxin is required for S-nitrosation of procaspase-3 and the inhibition of apoptosis in Jurkat cells
Douglas A. Mitchell et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Hyperglycemia regulates thioredoxin-ROS activity through induction of thioredoxin-interacting protein (TXNIP) in metastatic breast cancer-derived cells MDA-MB-231
Francesco Turturro et al.
BMC CANCER (2007)
Overexpression of thioredoxin1 in transgenic mice suppresses development of diabetic nephropathy
Yasuhiro Hamada et al.
NEPHROLOGY DIALYSIS TRANSPLANTATION (2007)
Thioredoxin1 as a negative regulator of cardiac hypertrophy
Tetsuro Ago et al.
ANTIOXIDANTS & REDOX SIGNALING (2007)
Structural determinants of the C-terminal helix-kink-helix motif essential for protein stability and survival promoting activity of DJ-1
Karin Goerner et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Does thioredoxin-1 prevent mitochondria- and endoplasmic reticulum-mediated neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine?
Jie Bai et al.
ANTIOXIDANTS & REDOX SIGNALING (2007)
Endothelial-specific expression of mitochondrial thioredoxin improves endothelial cell function and reduces atherosclerotic lesions
Haifeng Zhang et al.
AMERICAN JOURNAL OF PATHOLOGY (2007)
Buried S-nitrosocysteine revealed in crystal structures of human thioredoxin
Andrzej Weichsel et al.
BIOCHEMISTRY (2007)
Cyclophosphamide as a potent inhibitor of tumor thioredoxin reductase in vivo
Xufang Wang et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2007)
Impairment of thioredoxin reductase activity by oxidative stress in human rheumatoid synoviocytes
Herve Lemarechal et al.
FREE RADICAL RESEARCH (2007)
Strategies that modulate inflammasomes-insights from host-pathogen interactions
James B. Johnston et al.
SEMINARS IN IMMUNOPATHOLOGY (2007)
Prevalence of dementia in the united states: The aging, demographics, and memory study
B. L. Plassman et al.
NEUROEPIDEMIOLOGY (2007)
Inflammasome adaptors and sensors: intracellular regulators of infection and inflammation
Sanjeev Mariathasan et al.
NATURE REVIEWS IMMUNOLOGY (2007)
Thioredoxin and related molecules - From biology to health and disease
Christopher Horst Lillig et al.
ANTIOXIDANTS & REDOX SIGNALING (2007)
Free radicals and antioxidants in normal physiological functions and human disease
Marian Valko et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2007)
Spatial segregation of transport and signalling functions between human endothelial caveolae and lipid raft proteomes
Richard R. Sprenger et al.
BIOCHEMICAL JOURNAL (2006)
Mechanisms linking obesity to insulin resistance and type 2 diabetes
Steven E. Kahn et al.
NATURE (2006)
On the potential of thioredoxin reductase inhibitors for cancer therapy
Sabine Urig et al.
SEMINARS IN CANCER BIOLOGY (2006)
Extracellular thioredoxin and thioredoxin-binding protein 2 in control of cancer
Hajime Nakamura et al.
SEMINARS IN CANCER BIOLOGY (2006)
The thioredoxin system in cancer
Elias S. J. Arner et al.
SEMINARS IN CANCER BIOLOGY (2006)
Thioredoxin reductase is required for the inactivation of tumor suppressor p53 and for apoptosis induced by endogenous electrophiles
Pamela B. Cassidy et al.
CARCINOGENESIS (2006)
Thioredoxin interacting protein is increased in sensory neurons in experimental diabetes
Sally A. Price et al.
BRAIN RESEARCH (2006)
Selenocompounds can serve as oxidoreductants with the methionine sulfoxide reductase enzymes
Daphna Sagher et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Nitric oxide induces thioredoxin-1 nuclear translocation: Possible association with the p21Ras survival pathway
Roberto J. Arai et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Thioredoxin reduces post-ischemic myocardial apoptosis by reducing oxidative/nitrative stress
L. Tao et al.
BRITISH JOURNAL OF PHARMACOLOGY (2006)
The thioredoxin system in aging muscle: key role of mitochondrial thioredoxin reductase in the protective effects of caloric restriction?
Susanne Rohrbach et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2006)
Vitamin D3 upregulated protein 1 (VDUP1) is a regulator for redox signaling and stress-mediated diseases
Jin Woong Chung et al.
JOURNAL OF DERMATOLOGY (2006)
Nitrative inactivation of thioredoxin-1 and its role in postischemic myocardial apoptosis
Ling Tao et al.
CIRCULATION (2006)
The tert-butylhydroquinone-mediated activation of the human thioredoxin gene reveals a novel promoter structure
Simone A. Osborne et al.
BIOCHEMICAL JOURNAL (2006)
Involvement of glutaredoxin-1 and thioredoxin-1 in β-amyloid toxicity and Alzheimer's disease
S. Akterin et al.
CELL DEATH AND DIFFERENTIATION (2006)
Recombinant human thioredoxin suppresses lipopolysaccharide-induced bronchoalveolar neutrophil infiltration in rat
Shugo Ueda et al.
LIFE SCIENCES (2006)
The interaction of thioredoxin with Txnip - Evidence for formation of a mixed disulfide by disulfide exchange
Parth Patwari et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Hepatocellular carcinoma in Txnip-deficient mice
S. S. Sheth et al.
ONCOGENE (2006)
Extracellular thioredoxin levels are increased in patients with acute lung injury
M. E. Callister et al.
THORAX (2006)
Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data
Alan D. Lopez et al.
LANCET (2006)
Thioredoxin reductase as a novel molecular target for cancer therapy
Phuongmai Nguyen et al.
CANCER LETTERS (2006)
The antioxidant glutathione peroxidase family and spermatozoa: A complex story
Joel R. Drevet
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2006)
Thioredoxin reductase 1 deficiency reverses tumor phenotype and tumorigenicity of lung carcinoma cells
MH Yoo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
High redox thioredoxin but low thioredoxin reductase activities in the serum of patients with rheumatoid arthritis
H Lemarechal et al.
CLINICA CHIMICA ACTA (2006)
Oxidative damage of DJ-1 is linked to sporadic Parkinson and Alzheimer diseases
J Choi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Motexafin gadolinium, a tumor-selective drug targeting thioredoxin reductase and ribonucleotide reductase
SI Hashemy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Inhibition of mammalian thioredoxin reductase by some flavonoids: Implications for myricetin and quercetin anticancer activity
J Lu et al.
CANCER RESEARCH (2006)
Thioredoxin-mediated negative autoregulation of peroxisome proliferator-activated receptor α transcriptional activity
GH Liu et al.
MOLECULAR BIOLOGY OF THE CELL (2006)
Oxidative stress and vascular disease - 2005 Duff Lecture
DD Heistad
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2006)
Loss of interleukin-2-dependency in HTLV-I-infected T cells on gene silencing of thioredoxin-binding protein-2
MK Ahsan et al.
ONCOGENE (2006)
Thioredoxin-interacting protein (txnip) is a glucocorticoid-regulated primary response gene involved in mediating glucocorticoid-induced apoptosis
Z Wang et al.
ONCOGENE (2006)
Interactions of nitroaromatic compounds with the mammalian selenoprotein thioredoxin reductase and the relation to induction of apoptosis in human cancer cells
N Cenas et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Redox regulation of mast cell histamine release in thioredoxin-1 (TRX) transgenic mice
A Son et al.
CELL RESEARCH (2006)
Physiological and pathophysiological aspects of ceramide
E Gulbins et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2006)
Post-transcriptional regulation of thioredoxin by the stress inducible heterogenous ribonucleoprotein A18
RQ Yang et al.
NUCLEIC ACIDS RESEARCH (2006)
Redox regulation of human thioredoxin network
Norihiko Kondo et al.
ANTIOXIDANTS & REDOX SIGNALING (2006)
Thioredoxin-1 and posttranslational modifications
Judith Haendeler
ANTIOXIDANTS & REDOX SIGNALING (2006)
Matrix metalloproteinases: Role in arthritis
PS Burrage et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2006)
Thioredoxin-1 suppresses lung injury and apoptosis induced by diesel exhaust particles (DEP) by scavenging reactive oxygen species and by inhibiting DEP-induced downregulation of Akt
MK Ahsan et al.
FREE RADICAL BIOLOGY AND MEDICINE (2005)
Extracellular human thioredoxin-1 inhibits lipopolysaccharide-induced interleukin-1β expression in human monocyte-derived macrophages
L Billiet et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
cDNA microarray analysis reveals novel candidate genes expressed in human peripheral blood following exhaustive exercise
D Zieker et al.
PHYSIOLOGICAL GENOMICS (2005)
Gene expression profiling in INS-1 cells overexpressing thioredoxin-interacting protein
AH Minn et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Control of p53 nuclear accumulation in stressed cells
T Inoue et al.
FEBS LETTERS (2005)
Thioredoxin suppresses airway hyperresponsiveness and airway inflammation in asthma
H Ichiki et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Inhibition of thioredoxin reductase but not of glutathione reductase by the major classes of alkylating and platinum-containing anticancer compounds
AB Witte et al.
FREE RADICAL BIOLOGY AND MEDICINE (2005)
Thioredoxin catalyzes the S-nitrosation of the caspase-3 active site cysteine
DA Mitchell et al.
NATURE CHEMICAL BIOLOGY (2005)
Thioredoxin reductase is irreversibly modified by curcumin - A novel molecular mechanism for its anticancer activity
JG Fang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity
A Matsuzawa et al.
NATURE IMMUNOLOGY (2005)
Two distinct mechanisms for loss of thioredoxin-binding protein-2 in oxidative stress-induced renal carcinogenesis
KK Dutta et al.
LABORATORY INVESTIGATION (2005)
Aging-associated changes in cardiac gene expression
M Volkova et al.
CARDIOVASCULAR RESEARCH (2005)
Thioredoxin-interacting protein is stimulated by glucose through a carbohydrate response element and induces β-cell apoptosis
AH Minn et al.
ENDOCRINOLOGY (2005)
Differential activation of mitogenic signaling pathways in aortic smooth muscle cells deficient in superoxide dismutase isoforms
NR Madamanchi et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2005)
Histone deacetylase inhibitors in programmed cell death and cancer therapy
PA Marks et al.
CELL CYCLE (2005)
Oxidative stress-mediated, post-translational loss of MafA protein as a contributing mechanism to loss of insulin gene expression in glucotoxic beta cells
JS Harmon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Truncated thioredoxin (Trx80) induces differentiation of human CD14+ monocytes into a novel cell type (TAMs) via activation of the MAP kinases p38, ERK, and JNK
K Pekkari et al.
BLOOD (2005)
Oxidative stress in atherogenesis and arterial thrombosis: the disconnect between cellular studies and clinical outcomes
NR Madamanchi et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2005)
Cytotoxic and antiangiogenic activity of AW464 (NSC 706704), a novel thioredoxin inhibitor:: an in vitro study
A Mukherjee et al.
BRITISH JOURNAL OF CANCER (2005)
Role of thioredoxin in the response of normal and transformed cells to histone deacetylase inhibitors
JS Ungerstedt et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Inflammation in atherosclerosis: New opportunities for drug discovery
CQ Meng
MINI-REVIEWS IN MEDICINAL CHEMISTRY (2005)
Thioredoxin-interacting protein deficiency disrupts the fasting-feeding metabolic transition
SS Sheth et al.
JOURNAL OF LIPID RESEARCH (2005)
Curcumin, a major constituent of turmeric, corrects cystic fibrosis defects
ME Egan et al.
SCIENCE (2004)
Pharmacological induction of tolerogenic dendritic cells and regulatory T cells
L Adorini et al.
SEMINARS IN IMMUNOLOGY (2004)
Heat shock factor regulates VDUP1 gene expression
KY Kim et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
Loss of thioredoxin-binding protein-2/vitamin D3 up-regulated protein 1 in human T-cell leukemia virus type I-dependent T-Cell transformation: Implications for adult T-Cell leukemia leukemogenesis
Y Nishinaka et al.
CANCER RESEARCH (2004)
Mitochondrial thioredoxin reductase inhibition by gold(I) compounds and concurrent stimulation of permeability transition and release of cytochrome c
MP Rigobello et al.
BIOCHEMICAL PHARMACOLOGY (2004)
β-cell glucose toxicity, lipotoxicity, and chronic oxidative stress in type 2 diabetes
RP Robertson et al.
DIABETES (2004)
Truncated thioredoxin: Physiological functions and mechanism
K Pekkari et al.
ANTIOXIDANTS & REDOX SIGNALING (2004)
The mammalian testis-specific thioredoxin system
A Miranda-Vizuete et al.
ANTIOXIDANTS & REDOX SIGNALING (2004)
Up-regulation of the redox mediators thioredoxin and apurinic/apyrimidinic excision (APE)/ref-1 in hypoxic microregions of invasive cervical carcinomas, mapped using multispectral, wide-field fluorescence image analysis
D Hedley et al.
AMERICAN JOURNAL OF PATHOLOGY (2004)
Intravenous administration of thioredoxin decreases brain damage following transient focal cerebral ischemia in mice
I Hattori et al.
ANTIOXIDANTS & REDOX SIGNALING (2004)
Exercise training reduces neointimal growth and stabilizes vascular lesions developing after injury in apolipoprotein E-deficient mice
M Pynn et al.
CIRCULATION (2004)
Effects of exercise on gene expression in human peripheral blood mononuclear cells
PH Connolly et al.
JOURNAL OF APPLIED PHYSIOLOGY (2004)
Thioredoxin reductase as a potential molecular target for anticancer agents that induce oxidative stress
DDK Smart et al.
CANCER RESEARCH (2004)
Thioredoxin-1 binds to the C2 domain of PTEN inhibiting PTEN's lipid phosphatase activity and membrane binding: a mechanism for the functional loss of PTEN's tumor suppressor activity
EJ Meuillet et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2004)
Importin α1 (Rch1) mediates nuclear translocation of thioredoxin-binding protein-2/vitamin D3-up-regulated protein 1
Y Nishinaka et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Thioredoxin-1 ameliorates myosin-induced autoimmune myocarditis by suppressing chemokine expressions and leukocyte chemotaxis in mice
WR Liu et al.
CIRCULATION (2004)
Spermatocyte/spermatid-specific thioredoxin-3, a novel Golgi apparatus-associated thioredoxin, is a specific marker of aberrant spermatogenesis
A Jiménez et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Cardioprotective effects of thioredoxin in myocardial ischemia and the reperfusion role of S-nitrosation
L Tao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Hyperglycemia promotes oxidative stress through inhibition of thioredoxin function by thioredoxin-interacting protein
PC Schulze et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Estradiol regulates the thioredoxin antioxidant system in the mouse uterus
BJ Deroo et al.
ENDOCRINOLOGY (2004)
Thioredoxin modulates activator protein 1 (AP-1) activity and p27Kip1 degradation through direct interaction with Jab1
CY Hwang et al.
ONCOGENE (2004)
Thioredoxin-2 inhibits mitochondria-located ASK1-mediated apoptosis in a JNK-independent manner
R Zhang et al.
CIRCULATION RESEARCH (2004)
Mice lacking thioredoxin-interacting protein provide evidence linking cellular redox state to appropriate response to nutritional signals
TY Hui et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Thioredoxin-interacting protein controls cardiac hypertrophy through regulation of thioredoxin activity
J Yoshioka et al.
CIRCULATION (2004)
Thioredoxin as a neurotrophic cofactor and an important regulator of neuroprotection
H Masutani et al.
MOLECULAR NEUROBIOLOGY (2004)
Compartmentation of Nrf-2 redox control: Regulation of cytoplasmic activation by glutathione and DNA binding by thioredoxin-1
JM Hansen et al.
TOXICOLOGICAL SCIENCES (2004)
The thioredoxin system - From science to clinic
S Gromer et al.
MEDICINAL RESEARCH REVIEWS (2004)
Advances in protein kinase B signalling:: AKTion on multiple fronts
DP Brazil et al.
TRENDS IN BIOCHEMICAL SCIENCES (2004)
Increased skin carcinogenesis in a keratinocyte directed thioredoxin-1 transgenic mouse
D Mustacich et al.
CARCINOGENESIS (2004)
Exertional heat injury and gene expression changes: a DNA microarray analysis study
LA Sonna et al.
JOURNAL OF APPLIED PHYSIOLOGY (2004)
Thioredoxin liquefies and decreases the viscoelasticity of cystic fibrosis sputum
RC Rancourt et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2004)
Oxidative stress in cardiovascular disease: myth or fact?
C Ceconi et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2003)
Thioredoxin - A key regulator of cardiovascular homeostasis
H Yamawaki et al.
CIRCULATION RESEARCH (2003)
Thioredoxin-mediated redox control of the transcription factor Sp1 and regulation of the thioredoxin gene promoter
KL Bloomfield et al.
GENE (2003)
Redox regulation of PI 3-kinase signalling via inactivation of PTEN
NR Leslie et al.
EMBO JOURNAL (2003)
The role of thioredoxin in the aging process: Involvement of oxidative stress
T Yoshida et al.
ANTIOXIDANTS & REDOX SIGNALING (2003)
Preferential elevation of Prx I and Trx expression in lung cancer cells following hypoxia and in human lung cancer tissues
HJ Kim et al.
CELL BIOLOGY AND TOXICOLOGY (2003)
Protective roles of thioredoxin, a redox-regulating protein, in renal ischemia/reperfusion injury
K Kasuno et al.
KIDNEY INTERNATIONAL (2003)
Anti-inflammatory effects of exercise training in the skeletal muscle of patients with chronic heart failure
S Gielen et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2003)
Biological chemistry of reactive oxygen and nitrogen and radiation-induced signal transduction mechanisms
RB Mikkelsen et al.
ONCOGENE (2003)
Adenoviral transfection of hepatocytes with the thioredoxin gene confers protection against apoptosis and necrosis
T Tsutsui et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
S-nitrosylation of thioredoxin mediates activation of apoptosis signal-regulating kinase 1
VV Sumbayev
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2003)
Increased expression of thioredoxin-1 in human colorectal cancer is associated with decreased patient survival
J Raffel et al.
JOURNAL OF LABORATORY AND CLINICAL MEDICINE (2003)
Increased thioredoxin-1 inhibits SSAT expression in MCF-7 human breast cancer cells
B Husbeck et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
VDUP1 upregulated by TGF-β1 and 1,25-dihydorxyvitamin D3 inhibits tumor cell growth by blocking cell-cycle progression
SH Han et al.
ONCOGENE (2003)
Thioredoxin redox signaling in the ischemic heart: an insight with transgenic mice overexpressing Trx1
T Turoczi et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2003)
Elevated serum levels of thioredoxin in patients with acute exacerbation of asthma
Y Yamada et al.
IMMUNOLOGY LETTERS (2003)
Identification of metabolic enzymes in renal cell carcinoma utilizing PROTEOMEX analyses
R Lichtenfels et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2003)
4-substituted 4-hydroxycyclohexa-2,5-dien-1-ones with selective activities against colon and renal cancer cell lines
G Wells et al.
JOURNAL OF MEDICINAL CHEMISTRY (2003)
The absence of mitochondrial thioredoxin 2 causes massive apoptosis, exencephaly, and early embryonic lethality in homozygous mice
L Nonn et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Thioredoxin reductase and cancer cell growth inhibition by organotellurium antioxidants
L Engman et al.
ANTI-CANCER DRUGS (2003)
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism
V Bonifati et al.
SCIENCE (2003)
Expression of the thioredoxin system in interstitial lung disease
L Tiitto et al.
JOURNAL OF PATHOLOGY (2003)
Inhibition of endogenous thioredoxin in the heart increases oxidative stress and cardiac hypertrophy
M Yamamoto et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
Glucotoxicity and beta-cell failure in type 2 diabetes mellitus
N Kaiser et al.
JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM (2003)
The macrophage foam cell as a target for therapeutic intervention
AC Li et al.
NATURE MEDICINE (2002)
Vitamin D3-Upregulated protein-1 (VDUP-1) regulates redox-dependent vascular smooth muscle cell proliferation through interaction with thioredoxin
PC Schulze et al.
CIRCULATION RESEARCH (2002)
Selenoprotein expression in endothelial cells from different human vasculature and species
S Miller et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2002)
Oxidative stress, mitochondrial DNA mutation, and impairment of antioxidant enzymes in aging
YH Wei et al.
EXPERIMENTAL BIOLOGY AND MEDICINE (2002)
Redox regulatory and anti-apoptotic functions of thioredoxin depend on S-nitrosylation at cysteine 69
J Haendeler et al.
NATURE CELL BIOLOGY (2002)
Transglutaminase 2: an enigmatic enzyme with diverse functions
L Fesus et al.
TRENDS IN BIOCHEMICAL SCIENCES (2002)
Overexpression of thioredoxin-1 in transgenic mice attenuates adriamycin-induced cardiotoxicity
K Shioji et al.
CIRCULATION (2002)
Overexpressed human mitochondrial thioredoxin confers resistance to oxidant-induced apoptosis in human osteosarcoma cells
Y Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Human mitochondrial thioredoxin -: Involvement in mitochondrial membrane potential and cell death
AE Damdimopoulos et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
The histone deacetylase inhibitor SAHA arrests cancer cell growth, up-regulates thioredoxin-binding protein-2, and down-regulates thioredoxin
LM Butler et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Innate and adaptive immunity in the pathogenesis of atherosclerosis
GK Hansson et al.
CIRCULATION RESEARCH (2002)
Overexpression of human thioredoxin in transgenic mice controls oxidative stress and life span
A Mitsui et al.
ANTIOXIDANTS & REDOX SIGNALING (2002)
Glutathionylation of human thioredoxin: A possible crosstalk between the glutathione and thioredoxin systems
S Casagrande et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Cellular response to oxidative stress: Signaling for suicide and survival
JL Martindale et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2002)
Thioredoxin promotes ASK1 ubiquitination and degradation to inhibit ASK1-mediated apoptosis in a redox activity-independent manner
YM Liu et al.
CIRCULATION RESEARCH (2002)
Reversible inactivation of the tumor suppressor PTEN by H2O2
SR Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Enhanced resistancy of thioredoxin-transgenic mice against influenza virus-induced pneumonia
H Nakamura et al.
IMMUNOLOGY LETTERS (2002)
Thioredoxin suppresses 1-methyl-4-phenylpyridinium-induced neurotoxicity in rat PC12 cells
J Bai et al.
NEUROSCIENCE LETTERS (2002)
Cardiovascular diseases in the developing countries: dimensions, determinants, dynamics and directions for public health action
KS Reddy
PUBLIC HEALTH NUTRITION (2002)
Thioredoxin as a biomarker for oxidative stress in patients with rheumatoid arthritis
T Jikimoto et al.
MOLECULAR IMMUNOLOGY (2002)
Positional cloning of the combined hyperlipidemia gene Hyplip1
JS Bodnar et al.
NATURE GENETICS (2002)
Circulating thioredoxin suppresses lipopolysaccharide-induced neutrophil chemotaxis
H Nakamura et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Reactive oxygen species, antioxidants, and the mammalian thioredoxin system
J Nordberg et al.
FREE RADICAL BIOLOGY AND MEDICINE (2001)
The oxidative stress hypothesis of congestive heart failure - Radical thoughts
S Mak et al.
CHEST (2001)
Analysis of the inhibition of mammalian thioredoxin, thioredoxin reductase, and glutaredoxin by cis-diamminedichloroplatinum (II) and its major metabolite, the glutathione-platinum complex
ESJ Arnér et al.
FREE RADICAL BIOLOGY AND MEDICINE (2001)
Natural killer cells, viruses and cancer
A Cerwenka et al.
NATURE REVIEWS IMMUNOLOGY (2001)
Three-dimensional structure of a mammalian thioredoxin reductase: Implications for mechanism and evolution of a selenocysteine-dependent enzyme
T Sandalova et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
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