Related references
Note: Only part of the references are listed.Pharmacological ascorbate with gemcitabine for the control of metastatic and node-positive pancreatic cancer (PACMAN): results from a phase I clinical trial
J. L. Welsh et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2013)
Vitamin C in mouse and human red blood cells: An HPLC assay
Hongyan Li et al.
ANALYTICAL BIOCHEMISTRY (2012)
Pharmacological ascorbate induces cytotoxicity in prostate cancer cells through ATP depletion and induction of autophagy
Ping Chen et al.
ANTI-CANCER DRUGS (2012)
Natural resistance to ascorbic acid induced oxidative stress is mainly mediated by catalase activity in human cancer cells and catalase-silencing sensitizes to oxidative stress
Christoph Klingelhoeffer et al.
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE (2012)
Reactive oxygen species regulation of autophagy in cancer: Implications for cancer treatment
Lin Li et al.
FREE RADICAL BIOLOGY AND MEDICINE (2012)
Pharmacological concentrations of ascorbate radiosensitize glioblastoma multiforme primary cells by increasing oxidative DNA damage and inhibiting G2/M arrest
Patries M. Herst et al.
FREE RADICAL BIOLOGY AND MEDICINE (2012)
Enhanced antitumor activity of vitamin C via p53 in Cancer cells
Jinsun Kim et al.
FREE RADICAL BIOLOGY AND MEDICINE (2012)
Iron Overload in Human Disease
Robert E. Fleming et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
Phase I Evaluation of Intravenous Ascorbic Acid in Combination with Gemcitabine and Erlotinib in Patients with Metastatic Pancreatic Cancer
Daniel A. Monti et al.
PLOS ONE (2012)
Selective Ascorbate Toxicity in Malignant Mesothelioma A Redox Trojan Mechanism
Elia Ranzato et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2011)
The antioxidant ascorbic acid mobilizes nuclear copper leading to a prooxidant breakage of cellular DNA: implications for chemotherapeutic action against cancer
M. F. Ullah et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2011)
Ascorbate exerts anti-proliferative effects through cell cycle inhibition and sensitizes tumor cells towards cytostatic drugs
Anja Froemberg et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2011)
Anti-cancer effect of pharmacologic ascorbate and its interaction with supplementary parenteral glutathione in preclinical cancer models
Ping Chen et al.
FREE RADICAL BIOLOGY AND MEDICINE (2011)
Pharmacologic ascorbate synergizes with gemcitabine in preclinical models of pancreatic cancer
Michael Graham Espey et al.
FREE RADICAL BIOLOGY AND MEDICINE (2011)
Ascorbic Acid Enhances Radiation-induced Apoptosis in an HL60 Human Leukemia Cell Line
Koji Shinozaki et al.
JOURNAL OF RADIATION RESEARCH (2011)
Inhibitory Effect of Vitamin C in Combination With Vitamin K3 on Tumor Growth and Metastasis of Lewis Lung Carcinoma Xenografted in C57BL/6 Mice
Ming-Feng Chen et al.
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2011)
Pharmacologic Doses of Ascorbic Acid Repress Specificity Protein (Sp) Transcription Factors and Sp-Regulated Genes in Colon Cancer Cells
Satya S. Pathi et al.
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2011)
In vitro screening of synergistic ascorbate-drug combinations for the treatment of malignant mesothelioma
Simona Martinotti et al.
TOXICOLOGY IN VITRO (2011)
TRPA1 mediates spinal antinociception induced by acetaminophen and the cannabinoid Δ9-tetrahydrocannabiorcol
David A. Andersson et al.
NATURE COMMUNICATIONS (2011)
High dose of ascorbic acid induces cell death in mesothelioma cells
Yukitoshi Takemura et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
Pharmacologic concentrations of ascorbic acid cause diverse influence on differential expressions of angiogenic chemokine genes in different hepatocellular carcinoma cell lines
Zu-Yau Lin et al.
BIOMEDICINE & PHARMACOTHERAPY (2010)
H2O2-mediated Cytotoxicity of Pharmacologic Ascorbate Concentrations to Neuroblastoma Cells: Potential Role of Lactate and Ferritin
Beate Deubzer et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2010)
Mechanisms of Ascorbate-Induced Cytotoxicity in Pancreatic Cancer
Juan Du et al.
CLINICAL CANCER RESEARCH (2010)
Vitamin C transporter Slc23a1 links renal reabsorption, vitamin C tissue accumulation, and perinatal survival in mice
Christopher P. Corpe et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Vitamin C: Intravenous Use by Complementary and Alternative Medicine Practitioners and Adverse Effects
Sebastian J. Padayatty et al.
PLOS ONE (2010)
Comment re: Vitamin C Antagonizes the Cytotoxic Effects of Chemotherapy
Michael Graham Espey et al.
CANCER RESEARCH (2009)
Pharmacologic concentrations of ascorbate are achieved by parenteral administration and exhibit antitumoral effects
Julien Verrax et al.
FREE RADICAL BIOLOGY AND MEDICINE (2009)
Proteomic Analysis Reveals Upregulation of RKIP in S-180 Implanted BALB/C Mouse After Treatment With Ascorbic Acid
Seyeon Park et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2009)
High dose concentration administration of ascorbic acid inhibits tumor growth in BALB/C mice implanted with sarcoma 180 cancer cells via the restriction of angiogenesis
Chang-Hwan Yeom et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2009)
Ascorbic acid inhibits antitumor activity of bortezomib in vivo
G. Perrone et al.
LEUKEMIA (2009)
Antiproliferative Effect of Ascorbic Acid Is Associated with the Inhibition of Genes Necessary to Cell Cycle Progression
Sophie Belin et al.
PLOS ONE (2009)
Phase I clinical trial of i.v. ascorbic acid in advanced malignancy
L. J. Hoffer et al.
ANNALS OF ONCOLOGY (2008)
Vitamin C antagonizes the cytotoxic effects of antineoplastic drugs
Mark L. Heaney et al.
CANCER RESEARCH (2008)
Vitamin C suppresses proliferation of the human melanoma cell SK-MEL-2 through the inhibition of cyclooxygenase-2 (COX-2) expression and the modulation of insulin-like growth factor IIIGF-II production
Seung Koo Lee et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2008)
Anti-angiogenic effect of high doses of ascorbic acid
Nina A. Mikirova et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2008)
Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice
Qi Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
The molecular mechanisms of vitamin C on cell cycle regulation in B16F10 murine melanoma
Eunsil Hahm et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2007)
Sodium ascorbate induces apoptosis in neuroblastoma cell lines by interfering with iron uptake
Roberta Carosio et al.
MOLECULAR CANCER (2007)
Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid in vivo
Qi Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Changes of terminal cancer patients' health-related quality of life after high dose vitamin C administration
Chang Hwan Yeom et al.
JOURNAL OF KOREAN MEDICAL SCIENCE (2007)
Sodium ascorbate inhibits growth via the induction of cell cycle arrest and apoptosis in human malignant melanoma A375.S2 cells
Shuw-Yuan Lin et al.
MELANOMA RESEARCH (2006)
Intravenously administered vitamin C as cancer therapy: three cases
SJ Padayatty et al.
CANADIAN MEDICAL ASSOCIATION JOURNAL (2006)
Model organisms - The mighty mouse: genetically engineered mouse models in cancer drug development
Norman E. Sharpless et al.
NATURE REVIEWS DRUG DISCOVERY (2006)
Vitamin C enhances chemosensitization of esophageal cancer cells in vitro
MMM Abdel-Latif et al.
JOURNAL OF CHEMOTHERAPY (2005)
Pharmacologic ascorbic acid concentrations selectively kill cancer cells: Action as a pro-drug to deliver hydrogen peroxide to tissues
Q Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Phase I trial of menadiol diphosphate (vitamin K3) in advanced malignancy
D Lim et al.
INVESTIGATIONAL NEW DRUGS (2005)
Vitamin C pharmacokinetics: Implications for oral and intravenous use
SJ Padayatty et al.
ANNALS OF INTERNAL MEDICINE (2004)
L-ascorbic acid represses constitutive activation of NF-κB and COX-2 expression in human acute myeloid leukemia, HL-60
SS Han et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2004)
L-Ascorbic acid (vitamin C) induces the apoptosis of B16 murine melanoma cells via a caspase-8-independent pathway
JS Kang et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2003)
A new recommended dietary allowance of vitamin C for healthy young women
M Levine et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Ascorbic acid enhances arsenic trioxide-induced cytotoxicity in multiple myeloma cells
JM Grad et al.
BLOOD (2001)
The Haber-Weiss reaction and mechanisms of toxicity
JP Kehrer
TOXICOLOGY (2000)