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I kappa B kinase alpha-mediated derepression of SMRT potentiates acetylation of RelA/p65 by p300
JE Hoberg et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Redox-sensitive kinases of the nuclear factor-B-K signaling pathway
Cristen Pantano et al.
ANTIOXIDANTS & REDOX SIGNALING (2006)
Zinc dynamics in the myocardial redox signaling network
Irina Korichneva
ANTIOXIDANTS & REDOX SIGNALING (2006)
Zinc coordination environments in proteins as redox sensors and signal transducers
Wolfgang Maret
ANTIOXIDANTS & REDOX SIGNALING (2006)
Contribution of anti-inflammatory/immune suppressive processes to the pathology of sepsis
M Perl et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2006)
The antioxidant function of the p53 tumor suppressor
AA Sablina et al.
NATURE MEDICINE (2005)
The carboxy-terminal Neh3 domain of Nrf2 is required for transcriptional activation
P Nioi et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
2-Cys peroxiredoxin function in intracellular signal transduction: therapeutic implications
SW Kang et al.
TRENDS IN MOLECULAR MEDICINE (2005)
TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo
JH Shim et al.
GENES & DEVELOPMENT (2005)
Resolution of inflammation:: Prostaglandin E2 dissociates nuclear trafficking of individual NF-κB Subunits (p65, p50) in stimulated rheumatoid synovial fibroblasts
PF Gomez et al.
JOURNAL OF IMMUNOLOGY (2005)
Essential function for the kinase TAK1 in innate and adaptive immune responses
S Sato et al.
NATURE IMMUNOLOGY (2005)
Cloning and characterization of the human glutathione synthetase 5′-flanking region
TD Lee et al.
BIOCHEMICAL JOURNAL (2005)
Nuclear import and export signals in control of Nrf2
AK Jain et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Nrf2 possesses a redox-insensitive nuclear export signal overlapping with the leucine zipper motif
WG Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Reactive oxygen species in the control of hypoxia-inducible factor-mediated gene expression
T Kietzmann et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2005)
Differential responses of the Nrf2-Keap1 system to laminar and oscillatory shear stresses in endothelial cells
T Hosoya et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
NF-κB, Nrf2, and HO-1 interplay in redox-regulated VCAM-1 expression
A Banning et al.
ANTIOXIDANTS & REDOX SIGNALING (2005)
Peroxiredoxins: A historical overview and speculative preview of novel mechanisms and emerging concepts in cell signaling
SG Rhee et al.
FREE RADICAL BIOLOGY AND MEDICINE (2005)
Keap1 regulates the oxidation-sensitive shuttling of Nrf2 into and out of the nucleus via a Crm1-dependent nuclear export mechanism
M Velichkova et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
The GI-GPx gene is a target for Nrf2
A Banning et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Redox regulation of the transcriptional repressor Bach1
M Ishikawa et al.
FREE RADICAL BIOLOGY AND MEDICINE (2005)
Keap1, the sensor for electrophiles and oxidants that regulates the phase 2 response, is a zinc metalloprotein
AT Dinkova-Kostova et al.
BIOCHEMISTRY (2005)
Functions and mechanisms of redox regulation of cysteine-based phosphatases
A Salmeen et al.
ANTIOXIDANTS & REDOX SIGNALING (2005)
Peroxiredoxins, oxidative stress, and cell proliferation
S Immenschuh et al.
ANTIOXIDANTS & REDOX SIGNALING (2005)
Bach1 competes with Nrf2 leading to negative regulation of the antioxidant response element (ARE)-mediated NAD(P)H:quinone oxidoreductase 1 gene expression and induction in response to antioxidants
S Dhakshinamoorthy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
IKKα limits macrophage NF-κB activation and contributes to the resolution of inflammation
T Lawrence et al.
NATURE (2005)
Role that phosphorylation of GSK3 plays in insulin
EJ McManus et al.
EMBO JOURNAL (2005)
Structural mechanism of oxidative regulation of the phosphatase Cdc25B via an intramolecular disulfide bond
G Buhrman et al.
BIOCHEMISTRY (2005)
Intracellular messenger function of hydrogen peroxide and its regulation by peroxiredoxins
SG Rhee et al.
CURRENT OPINION IN CELL BIOLOGY (2005)
Epithelium-specific glutathione peroxidase, Gpx2, is involved in the prevention of intestinal inflammation in selenium-deficient mice
RS Esworthy et al.
JOURNAL OF NUTRITION (2005)
PTPs versus PTKs: The redox side of the coin
P Chiarugi
FREE RADICAL RESEARCH (2005)
Extremely potent triterpenoid inducers of the phase 2 response: Correlations of protection against oxidant and inflammatory stress
AT Dinkova-Kostova et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Protein kinase Cδ regulates p67phox phosphorylation in human monocytes
XX Zhao et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2005)
Tyrosine nitration on p65 -: A novel mechanism to rapidly inactivate nuclear factor-κB
SW Park et al.
MOLECULAR & CELLULAR PROTEOMICS (2005)
Peroxiredoxin-mediated redox regulation of the nuclear localization of Yap1, a transcription factor in budding yeast
S Okazaki et al.
ANTIOXIDANTS & REDOX SIGNALING (2005)
Redox regulation of NF-κB activation:: Distinct redox regulation between the cytoplasm and the nucleus
Y Kabe et al.
ANTIOXIDANTS & REDOX SIGNALING (2005)
TNF receptor (TNFR)-associated factor (TRAF) 3 serves as an inhibitor of TRAF2/5-mediated activation of the noncanonical NF-κB pathway by TRAF-binding TNFRs
J Hauer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Redox control of catalytic activities of membrane-associated protein tyrosine kinases
I Nakashima et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2005)
Nuclear oncoprotein prothymosin α is a partner of Keap1:: Implications for expression of oxidative stress-protecting genes
RN Karapetian et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Phosphorylation of NF-kappa B and I kappa B proteins: implications in cancer and inflammation
P Viatour et al.
TRENDS IN BIOCHEMICAL SCIENCES (2005)
Function and regulation of Cullin-RING ubiquitin ligases
MD Petroski et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)
BTB protein keap1 targets antioxidant transcription factor nrf2 for ubiquitination by the cullin 3-Roc1 ligase
M Furukawa et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Shaping the nuclear action of NF-κB
LF Chen et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2004)
A Fenton reaction at the endoplasmic reticulum is involved in the redox control of hypoxia-inducible gene expression
Q Liu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Role of Nrf2 in the regulation of CD36 and stress protein expression in murine macrophages - Activation by oxidatively modified LDL and 4-hydroxynonenal
T Ishii et al.
CIRCULATION RESEARCH (2004)
Regulation of heme oxygenase-1 expression through the phosphatidylinositol 3-kinase/Akt pathway and the Nrf2 transcription factor in response to the antioxidant phytochemical carnosol
D Martin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Cellular mechanisms of redox cell signalling: role of cysteine modification in controlling antioxidant defences in response to electrophilic lipid oxidation products
AL Levonen et al.
BIOCHEMICAL JOURNAL (2004)
Specific excision of the selenocysteine tRNA[Ser]Sec (Trsp) gene in mouse liver demonstrates an essential role of selenoproteins in liver function
BA Carlson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Scaffolding of Keap1 to the actin cytoskeleton controls the function of Nrf2 as key regulator of cytoprotective phase 2 genes
MI Kang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Protection against electrophile and oxidant stress by induction of the phase 2 response: Fate of cysteines of the Keap1 sensor modified by inducers
N Wakabayashi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Modulation of the redox state of tubulin by the glutathione/glutaredoxin reductase system
LM Landino et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
p47phox deficiency impairs NF-κB activation and host defense in Pseudomonas pneumonia
RT Sadikot et al.
JOURNAL OF IMMUNOLOGY (2004)
Identification and characterization of TRP14, a thioredoxin-related protein of 14 kDa - New insights into the specificity of thioredoxin function
W Jeong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Roles of TRP14, a thioredoxin-related protein in tumor necrosis factor-α signaling pathways
W Jeong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Cytosolic peroxiredoxin attenuates the activation of JNK and p38 but potentiates that of ERK in HeLa cells stimulated with tumor necrosis factor-α
SW Kang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Protein phosphatase 2Cβ association with the IκB kinase complex is involved in regulating NF-κB activity
S Prajapati et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
NF-κB functions as a tumour promoter in inflammation-associated cancer
E Pikarsky et al.
NATURE (2004)
Cutting edge:: Direct interaction of TLR4 with NAD(P)H oxidase 4 isozyme is essential for lipopolysaccharide-induced production of reactive oxygen species and activation of NF-κB
HS Park et al.
JOURNAL OF IMMUNOLOGY (2004)
Recruitment of NF-κB into mitochondria is involved in adenine nucleotide translocase 1 (ANT1)-induced apoptosis
M Zamora et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Inhibition of NF-κB in cancer cells converts inflammation-induced tumor growth mediated by TNFα to TRAIL-mediated tumor regression
JL Luo et al.
CANCER CELL (2004)
A new role of protein phosphatase 2A in adenoviral E1A protein-mediated sensitization to anticancer drug-induced apoptosis in human breast cancer cells
Y Liao et al.
CANCER RESEARCH (2004)
Trypanosoma brucei and Trypanosoma cruzi tryparedoxin peroxidases catalytically detoxify peroxynitrite via oxidation of fast reacting thiols.
M Trujillo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
IKKβ links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
FR Greten et al.
CELL (2004)
Distinct roles of c-Abl and Atm in oxidative stress response are mediated by protein kinase C δ
BJ Li et al.
GENES & DEVELOPMENT (2004)
Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate for proteasomal degradation of Nrf2
A Kobayashi et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Redox signaling: thiol chemistry defines which reactive oxygen and nitrogen species can act as second messengers
HJ Forman et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2004)
Human peroxiredoxin 5 is a peroxynitrite reductase
M Dubuisson et al.
FEBS LETTERS (2004)
Redox-regulated turnover of Nrf2 is determined by at least two separate protein domains, the redox-sensitive Neh2 degron and the redox-insensitive Neh6 degron
M McMahon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex
DD Zhang et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Degradation of promoter-bound p65/RelA is essential for the prompt termination of the nuclear factor κB response
S Saccani et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2004)
A 2-Cys peroxiredoxin regulates peroxide-induced oxidation and activation of a stress-activated MAP kinase
EA Veal et al.
MOLECULAR CELL (2004)
Ubiquitin: structures, functions, mechanisms
CM Pickart et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2004)
Phosphorylation of serine 468 by GSK-3β negatively regulates basal p65 NF-κB activity
H Buss et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Structural basis of cellular redox regulation by human TRP14
JR Woo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
p53 induces NF-κB activation by an IκB kinase-independent mechanism involving phosphorylation of p65 by ribosomal S6 kinase 1
J Bohuslav et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Suppression of MEK/ERK signaling pathway enhances cisplatin-induced NF-κB activation by protein phosphatase 4-mediated NF-κB p65 Thr dephosphorylation
PY Yeh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
The two NF-κB activation pathways and their role in innate and adaptive immunity
G Bonizzi et al.
TRENDS IN IMMUNOLOGY (2004)
Protein kinase Cδ is required for P47phox phosphorylation and translocation in activated human monocytes
EA Bey et al.
JOURNAL OF IMMUNOLOGY (2004)
Protein thiol modification by 15-deoxy-Δ12,14-prostaglandin J2 addition in mesangial cells:: Role in the inhibition of pro-inflammatory genes
FJ Sánchez-Gómez et al.
MOLECULAR PHARMACOLOGY (2004)
Transcription factor Nrf2 regulates inflammation by mediating the effect of 15-deoxy-Delta(12),(14)-prostaglandin J(2)
K Itoh et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice
T Rangasamy et al.
JOURNAL OF CLINICAL INVESTIGATION (2004)
Compartmentation of Nrf-2 redox control: Regulation of cytoplasmic activation by glutathione and DNA binding by thioredoxin-1
JM Hansen et al.
TOXICOLOGICAL SCIENCES (2004)
Ubiquitin ligases and the immuneresponse
YC Liu
ANNUAL REVIEW OF IMMUNOLOGY (2004)
Molecular mechanisms of endotoxin tolerance
HK Fan et al.
JOURNAL OF ENDOTOXIN RESEARCH (2004)
Two enzymes in one: Two yeast peroxiredoxins display oxidative stress-dependent switching from a peroxidase to a molecular chaperone function
HH Jang et al.
CELL (2004)
Regulation of Nrf2 transactivation domain activity - The differential effects of mitogen-activated protein kinase cascades and synergistic stimulatory effect of Raf and CREB-binding protein
GX Shen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Transient and selective NF-κB p65 serine 536 phosphorylation induced by T cell costimulation is mediated by IκB kinase β and controls the kinetics of p65 nuclear import
I Mattioli et al.
JOURNAL OF IMMUNOLOGY (2004)
Glutaredoxin exerts an antiapoptotic effect by regulating the redox state of Akt
H Murata et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Phosphorylation of Nrf2 at Ser40 by protein kinase C in response to antioxidants leads to the release of Nrf2 from INrf2, but is not required for Nrf2 stabilization/accumulation in the nucleus and transcriptional activation of antioxidant response element-mediated NAD(P)H:quinone oxidoreductase-1 gene expression
DA Bloom et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Transcription factor Nrf2 is required for the constitutive and inducible expression of multidrug resistance-associated protein 1 in mouse embryo fibroblasts
A Hayashi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
The role of glutathione-S-transferase in anti-cancer drug resistance
DM Townsend et al.
ONCOGENE (2003)
Redox regulation of PI 3-kinase signalling via inactivation of PTEN
NR Leslie et al.
EMBO JOURNAL (2003)
Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival
SB Cullinan et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Catalytic and chemical competence of regulation of Cdc25 phosphatase by oxidation/reduction
J Sohn et al.
BIOCHEMISTRY (2003)
Regulation of distinct biological activities of the NF-κB transcription factor complex by acetylation
LF Chen et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2003)
Atypical protein kinase C mediates activation of NF-E2-related factor 2 in response to oxidative stress
S Numazawa et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2003)
Essential role of RelA Ser311 phosphorylation by ζPKC in NF-κB transcriptional activation
A Duran et al.
EMBO JOURNAL (2003)
Role of the phosphatidylinositol 3 kinase-Akt pathway in the regulation of IL-10 and IL-12 by Porphyromonas gingivalis lipopolysaccharide
M Martin et al.
JOURNAL OF IMMUNOLOGY (2003)
Regulation of cell death: The calcium-apoptosis link
S Orrenius et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2003)
Evidence that reactive oxygen species do not mediate NF-κB activation
M Hayakawa et al.
EMBO JOURNAL (2003)
Hydrogen peroxide activates NF-κB through tyrosine phosphorylation of IκBα and serine phosphorylation of p65 -: Evidence for the involvement of IκBα kinase and Syk protein-tyrosine kinase
Y Takada et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Activation of nuclear receptors by prostaglandins
T Ide et al.
THROMBOSIS RESEARCH (2003)
Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression
M McMahon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Redox regulation of protein tyrosine phosphatase 1B involves a sulphenyl-amide intermediate
A Salmeen et al.
NATURE (2003)
Oxidation state of the active-site cysteine in protein tyrosine phosphatase 1B
RLM van Montfort et al.
NATURE (2003)
Collaborative induction of inflammatory responses by dectin-1 and toll-like receptor 2
BN Gantner et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Peroxiredoxin evolution and the regulation of hydrogen peroxide signaling
ZA Wood et al.
SCIENCE (2003)
Lymphotoxin β receptor induces sequential activation of distinct NF-κB factors via separate signaling pathways
JR Müller et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Versatility of selenium catalysis in PHGPx unraveled by LC/ESI-MS/MS
P Mauri et al.
BIOLOGICAL CHEMISTRY (2003)
Microflora trigger colitis in mice deficient in selenium-dependent glutathione peroxidase and induce Gpx2 gene expression
RS Esworthy et al.
BIOLOGICAL CHEMISTRY (2003)
Transcriptional activation of the NF-κB p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1)
L Vermeulen et al.
EMBO JOURNAL (2003)
Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway - Identification of novel gene clusters for cell survival
MK Kwak et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
An integrated stress response regulates amino acid metabolism and resistance to oxidative stress
HP Harding et al.
MOLECULAR CELL (2003)
Increased protein stability as a mechanism that enhances Nrf2-mediated transcriptional activation of the antioxidant response element - Degradation of Nrf2 by the 26 S proteasome
T Nguyen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Nrf2 mediates the induction of ferritin H in response to xenobiotics and cancer chemopreventive dithiolethiones
EC Pietsch et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Targeting of protein ubiquitination by BTB-Cullin 3-Roc1 ubiquitin ligases
M Furukawa et al.
NATURE CELL BIOLOGY (2003)
Antioxidants enhance mammalian proteasome expression through the Keap1-Nrf2 signaling pathway
MK Kwak et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress
DD Zhang et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Endotoxin tolerance: is there a clinical relevance?
JM Cavaillon et al.
JOURNAL OF ENDOTOXIN RESEARCH (2003)
Structural and functional characterization of the Pseudomonas hydroperoxide resistance protein Ohr
J Lesniak et al.
EMBO JOURNAL (2002)
Trends in selenium biochemistry
M Birringer et al.
NATURAL PRODUCT REPORTS (2002)
Antioxidant regulation of protein kinase C in cancer prevention
R Gopalakrishna et al.
JOURNAL OF NUTRITION (2002)
Electrophile response element-mediated induction of the cystine/glutamate exchange transporter gene expression
H Sasaki et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Spatial redox regulation of a critical cysteine residue of NF-κB in vivo
T Nishi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Zinc release from protein kinase C as the common event during activation by lipid second messenger or reactive oxygen
I Korichneva et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
A thiol peroxidase is an H2O2 receptor and redox-transducer in gene activation
A Delaunay et al.
CELL (2002)
Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription
HC Huang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Phosphatidylinositol 3-kinase regulates nuclear translocation of NF-E2-related factor 2 through actin rearrangement in response to oxidative stress
KW Kang et al.
MOLECULAR PHARMACOLOGY (2002)
Phenylethyl isothiocyanate induces apoptotic signaling via suppressing phosphatase activity against c-Jun N-terminal kinase
YR Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
The Keap1 BTB/POZ dimerization function is required to sequester Nrf2 in cytoplasm
LM Zipper et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Oxidoreductive modification of two cysteine residues in paired domain by Ref-1 regulates DNA-binding activity of Pax-8
X Cao et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)
Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants
AT Dinkova-Kostova et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
A universal role for MyD88 in TLR/IL-1R-mediated signaling
S Janssens et al.
TRENDS IN BIOCHEMICAL SCIENCES (2002)
All signaling is local?
J Schlessinger
MOLECULAR CELL (2002)
Regulation of peroxiredoxin I activity by Cdc2-mediated phosphorylation
TS Chang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Regulation of inducible peroxide stress responses
S Mongkolsuk et al.
MOLECULAR MICROBIOLOGY (2002)
Activation of c-Raf kinase by ultraviolet light
B Hoyos et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Reversible inactivation of the tumor suppressor PTEN by H2O2
SR Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Redox state of tumor suppressor p53 regulates its sequence-specific DNA binding in DNA-damaged cells by cysteine 277
J Buzek et al.
NUCLEIC ACIDS RESEARCH (2002)
Hydrogen peroxide activates IκB kinases through phosphorylation of serine residues in the activation loops
H Kamata et al.
FEBS LETTERS (2002)
Gene expression - Emerging roles of ubiquitin in transcription regulation
RC Conaway et al.
SCIENCE (2002)
Enhanced expression of the transcription factor Nrf2 by cancer chemopreventive agents:: Role of antioxidant response element-like sequences in the nrf2 promoter
MK Kwak et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Site-directed mutagenesis of cysteine to serine in the DNA binding region of Nrf2 decreases its capacity to upregulate antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene
D Bloom et al.
ONCOGENE (2002)
NF-kappa B at the crossroads of life and death
M Karin et al.
NATURE IMMUNOLOGY (2002)
The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1
HH Zhong et al.
MOLECULAR CELL (2002)
Identification of cysteine sulfenic acid in AhpC of alkyl hydroperoxide reductase
LB Poole et al.
PROTEIN SENSORS AND REACTIVE OXYGEN SPECIES, PT B, THIOL ENZYMES AND PROTEINS (2002)
A human homologue of Drosophila Kelch associates with myosin-VIIa in speciaiized adhesion junctions
M Velichkova et al.
CELL MOTILITY AND THE CYTOSKELETON (2002)
Reversible glutathionylation regulates actin polymerization in A431 cells
J Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Glutathionylation of the p50 subunit of NF-κB:: a mechanism for redox-induced inhibition of DNA binding
E Pineda-Molina et al.
BIOCHEMISTRY (2001)
Functional characterization of transcription regulators that interact with the electrophile response element
M Zhu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
Targeted disruption of the ζPKC gene results in the impairment of the NF-κB pathway
M Leitges et al.
MOLECULAR CELL (2001)
Impaired pulmonary NF-κB activation in response to lipopolysaccharide in NADPH oxidase-deficient mice
MA Koay et al.
INFECTION AND IMMUNITY (2001)
Cytokine-induced activation of nuclear factor-κB is inhibited by hydrogen peroxide through oxidative inactivation of IκB kinase
SH Korn et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Peroxynitrite-induced tyrosine nitration and inhibition of protein kinase C
LT Knapp et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
Activation by IKKα of a second, evolutionary conserved, NF-κB signaling pathway
U Senftleben et al.
SCIENCE (2001)
Oxidation of zinc finger transcription factors: Physiological consequences
KA Webster et al.
ANTIOXIDANTS & REDOX SIGNALING (2001)
The PX domains of p47phox and p40phox bind to lipid products of Pl(3)K
F Kanai et al.
NATURE CELL BIOLOGY (2001)
Ptdlns(3)P regulates the neutrophil oxidase complex by binding to the PX domain of p40phox
CD Ellson et al.
NATURE CELL BIOLOGY (2001)
Akt stimulates the transactivation potential of the RelA/p65 subunit of NF-κB through utilization of the IκB kinase and activation of the mitogen-activated protein kinase p38
LV Madrid et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Potency of Michael reaction accepters as inducers of enzymes that protect against carcinogenesis depends on their reactivity with sulfhydryl groups
AT Dinkova-Kostova et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice
M Ramos-Gomez et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Inflammation and cancer: back to Virchow?
F Balkwill et al.
LANCET (2001)
Evolution of selenocysteine-containing proteins: Significance of identification and functional characterization of selenoproteins
VN Gladyshev et al.
BIOFACTORS (2001)
The p50-homodimer mechanism in tolerance to LPS
L Ziegler-Heitbrock
JOURNAL OF ENDOTOXIN RESEARCH (2001)
Small Maf (MafG and MafK) proteins negatively regulate antioxidant response element-mediated expression and antioxidant induction of the NAD(P)H:quinone oxidoreductase1 gene
S Dhakshinamoorthy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Activation of mitogen-activated protein kinase pathways induces antioxidant response element-mediated gene expression via a Nrf2-dependent mechanism
R Yu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Oxidants, oxidative stress and the biology of ageing
T Finkel et al.
NATURE (2000)
Nuclear factor-κB, cancer, and apoptosis
V Bours et al.
BIOCHEMICAL PHARMACOLOGY (2000)
Cell signaling by receptor tyrosine kinases
J Schlessinger
CELL (2000)
Overexpression of PHGPx inhibits hydroperoxide-induced oxidation, NFκB activation and apoptosis and affects oxLDL-mediated proliferation of rabbit aortic smooth muscle cells
R Brigelius-Flohé et al.
ATHEROSCLEROSIS (2000)
Coordinate transcriptional and translational regulation of ferritin in response to oxidative stress
Y Tsuji et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
Thioredoxin peroxidase is required for the transcriptional response to oxidative stress in budding yeast
SJ Ross et al.
MOLECULAR BIOLOGY OF THE CELL (2000)
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