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Molecular mechanisms of aging-associated inflammation
Devanand Sarkar et al.
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Malnutrition and energy restriction differentially affect viral immunity
BW Ritz et al.
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Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells
K Ito et al.
NATURE MEDICINE (2006)
Keratinocyte growth factor (KGF) is required for postnatal thymic regeneration
Ö Alpdogan et al.
BLOOD (2006)
The molecular inflammatory process in aging
Hae Young Chung et al.
ANTIOXIDANTS & REDOX SIGNALING (2006)
TOR signaling in growth and metabolism
S Wullschleger et al.
CELL (2006)
Chaperone-related immune dysfunction:: an emergent property of distorted chaperone networks
G Nardai et al.
TRENDS IN IMMUNOLOGY (2006)
TOR signaling in growth and metabolism
Stephan Wullschleger et al.
CELL (2006)
Inflammation markers predicting frailty and mortality in the elderly
Massimo De Martinis et al.
EXPERIMENTAL AND MOLECULAR PATHOLOGY (2006)
The thymus is a common target organ in infectious diseases
Wilson Savino
PLOS PATHOGENS (2006)
The epigenetic progenitor origin of human cancer
AP Feinberg et al.
NATURE REVIEWS GENETICS (2006)
A developmental timing microRNA and its target regulate life span in C. elegans
M Boehm et al.
SCIENCE (2005)
The role of low molecular weight thiols in T lymphocyte proliferation and IL-2 secretion
T Hadzic et al.
JOURNAL OF IMMUNOLOGY (2005)
Secretion of IFN-γ and not IL-2 by anergic human T cells correlates with assembly of an immature immune synapse
LM Carlin et al.
BLOOD (2005)
Developments in ghrelin biology and potential clinical relevance
RG Smith et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2005)
Mice and flies and monkeys too: Caloric restriction rejuvenates the aging immune system of non-human primates
J Nikolich-Zugich et al.
EXPERIMENTAL GERONTOLOGY (2005)
Ghrelin and immunity: A young player in an old field
VD Dixit et al.
EXPERIMENTAL GERONTOLOGY (2005)
Genomic stability and functional activity may be lost in telomerase-transduced human CD8+ T lymphocytes
MWJ Schreurs et al.
BLOOD (2005)
The aging innate immune system
CR Gomez et al.
CURRENT OPINION IN IMMUNOLOGY (2005)
Autophagy and aging -: The importance of maintaining clean cells
Ana Maria Cuervo et al.
AUTOPHAGY (2005)
Nrf2 controls constitutive and inducible expression of ARE-driven genes through a dynamic pathway involving nucleocytoplasmic shuttling by Keap1
T Nguyen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Redox equilibrium in mucosal T cells tunes the intestinal TCR signaling threshold
BMR Reyes et al.
JOURNAL OF IMMUNOLOGY (2005)
The impact of telomere erosion on memory CD8+ T cells in patients with X-linked lymphoproliferative syndrome
FJ Plunkett et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2005)
Protein degradation and aging
M Martinez-Vicente et al.
EXPERIMENTAL GERONTOLOGY (2005)
Aberrant T cell differentiation in the absence of Dicer
SA Muljo et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Genomic instability in laminopathy-based premature aging
BH Liu et al.
NATURE MEDICINE (2005)
Inhibition of NF-κB and oxidative pathways in human dendritic cells by antioxidative vitamins generates regulatory T cells
PH Tan et al.
JOURNAL OF IMMUNOLOGY (2005)
The influence of age on T cell generation and TCR diversity
K Naylor et al.
JOURNAL OF IMMUNOLOGY (2005)
Post-thymic in vivo proliferation of naive CD4+ T cells constrains the TCR repertoire in healthy human adults
S Kohler et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2005)
Autophagy promotes MHC class II presentation of peptides from intracellular source proteins
J Dengjel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Calorie restriction, SIRT1 and metabolism: Understanding longevity
L Bordone et al.
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Overexpression of proteasome β5 subunit increases the amount of assembled proteasome and confers ameliorated response to oxidative stress and higher survival rates
N Chondrogianni et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Long-term cytomegalovirus infection leads to significant changes in the composition of the CD8+ T-cell repertoire, which may be the basis for an imbalance in the cytokine production profile in elderly persons
G Almanzar et al.
JOURNAL OF VIROLOGY (2005)
DNA repair, genome stability, and aging
DB Lombard et al.
CELL (2005)
Lifespan extension and elevated hsp gene expression in Drosophila caused by histone deacetylase inhibitors
YM Zhao et al.
JOURNAL OF EXPERIMENTAL BIOLOGY (2005)
Proteolysis: from the lysosome to ubiquitin and the proteasome
A Ciechanover
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)
The molecular machinery of autophagy: unanswered questions
DJ Klionsky
JOURNAL OF CELL SCIENCE (2005)
MacrophAging: A cellular and molecular review
C Sebastian et al.
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TNFα induces rapid activation and nuclear translocation of telomerase in human lymphocytes
M Akiyama et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
Development by self-digestion: Molecular mechanisms and biological functions of autophagy
B Levine et al.
DEVELOPMENTAL CELL (2004)
Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid
JH Suh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaks
OA Sedelnikova et al.
NATURE CELL BIOLOGY (2004)
Tapasin and other chaperones: models of the MHC class I loading complex
CA Wright et al.
BIOLOGICAL CHEMISTRY (2004)
Impaired innate immunity predicts frailty in old age.: The Leiden 85-plus study
AHJ van den Biggelaar et al.
EXPERIMENTAL GERONTOLOGY (2004)
Bone marrow microenvironmental changes underlie reduced RAG-mediated recombination and B cell generation in aged mice
JE Labrie et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2004)
Genetic dissection of systemic autoimmune disease in Nrf2-deficient mice
J Li et al.
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Innate immunity in aging: impact on macrophage function
J Plowden et al.
AGING CELL (2004)
The cellular response to general and programmed DNA double strand breaks
CH Bassing et al.
DNA REPAIR (2004)
Signal transduction and functional changes in neutrophils with aging
T Fulop et al.
AGING CELL (2004)
Degradation of promoter-bound p65/RelA is essential for the prompt termination of the nuclear factor κB response
S Saccani et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2004)
Altered proteasome function and subunit composition in aged muscle
AD Husom et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2004)
Cutting edge: Cross-presentation of cell-associated antigens to MHC class I molecule is regulated by a major transcription factor for heat shock proteins
H Zheng et al.
JOURNAL OF IMMUNOLOGY (2004)
Modulation of NF-κB-dependent transcription and cell survival by the SIRT1 deacetylase
F Yeung et al.
EMBO JOURNAL (2004)
Nrf2-Keap1 defines a physiologically important stress response mechanism
H Motohashi et al.
TRENDS IN MOLECULAR MEDICINE (2004)
T cell receptor stimulation, reactive oxygen species, and cell signaling
MS Williams et al.
FREE RADICAL BIOLOGY AND MEDICINE (2004)
Impact of genome instability on transcription regulation of aging and senescence
J Vijg
MECHANISMS OF AGEING AND DEVELOPMENT (2004)
A DNA damage checkpoint response in telomere-initiated senescence
FD di Fagagna et al.
NATURE (2003)
Transcriptional control of the DNA methyltransferases is altered in aging and neoplastically-transformed human fibroblasts
MA Casillas et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2003)
Aging and molecular chaperones
C Soti et al.
EXPERIMENTAL GERONTOLOGY (2003)
The free radical theory of aging
D Harman
ANTIOXIDANTS & REDOX SIGNALING (2003)
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
KT Howitz et al.
NATURE (2003)
Elevated levels of tumor necrosis factor alpha and mortality in centenarians
H Bruunsgaard et al.
AMERICAN JOURNAL OF MEDICINE (2003)
Relief of oxidative stress by ascorbic acid delays cellular senescence of normal human and Werner syndrome fibroblast cells
G Kashino et al.
FREE RADICAL BIOLOGY AND MEDICINE (2003)
T cell receptor-stimulated generation of hydrogen peroxide inhibits MEK-ERK activation and lck serine phosphorylation
J Kwon et al.
FREE RADICAL BIOLOGY AND MEDICINE (2003)
Oxidative-stress-induced T lymphocyte hyporesponsiveness is caused by structural modification rather than proteasomal degradation of crucial TCR signaling molecules
S Cemerski et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2003)
Age-associated accumulation of CMV-specitic CD8+ T cells expressing the inhibitory killer cell lectin-like receptor G1 (KLRG1)
OY Qin et al.
EXPERIMENTAL GERONTOLOGY (2003)
Recurrent de novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome
M Eriksson et al.
NATURE (2003)
Stable telomere length and telomerase expression from naive to memory B-lymphocyte differentiation
NH Son et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2003)
Neutrophil immunity of the elderly
AK Schröder et al.
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An age-related increase in the number of CD8+ T cells carrying receptors for an immunodominant Epstein-Barr virus (EBV) epitope is counteracted by a decreased frequency of their antigen-specific responsiveness
Q Ouyang et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2003)
Ceramide-induced and age-associated increase in macrophage COX-2 expression is mediated through up-regulation of NF-κB activity
DY Wu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Increased protein stability as a mechanism that enhances Nrf2-mediated transcriptional activation of the antioxidant response element - Degradation of Nrf2 by the 26 S proteasome
T Nguyen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Germinal center B cells in Peyer's patches of aged mice exhibit a normal activation phenotype and highly mutated IgM genes
BJ Rogerson et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2003)
Oxidative inactivation of CD45 protein tyrosine phosphatase may contribute to T lymphocyte dysfunction in the elderly
DA Rider et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2003)
Enhanced differentiation of splenic plasma cells but diminished long-lived high-affinity bone marrow plasma cells in aged mice
SS Han et al.
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Degradation of transcription factor Nrf2 via the ubiquitin-proteasome pathway and stabilization by cadmium
D Stewart et al.
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DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells
MF Robert et al.
NATURE GENETICS (2003)
Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation
N Wakabayashi et al.
NATURE GENETICS (2003)
Antioxidants enhance mammalian proteasome expression through the Keap1-Nrf2 signaling pathway
MK Kwak et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Aging, cancer and nutrition: the DNA methylation connection
L Liu et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2003)
Molecular inflammation hypothesis of aging based on the anti-aging mechanism of calorie restriction
HY Chung et al.
MICROSCOPY RESEARCH AND TECHNIQUE (2002)
Circulating, interferon-producing plasmacytoid dendritic cells decline during human ageing
M Shodell et al.
SCANDINAVIAN JOURNAL OF IMMUNOLOGY (2002)
Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
A Mantovani et al.
TRENDS IN IMMUNOLOGY (2002)
Postsynthetic trimethylation of histone H4 at lysine 20 in mammalian tissues is associated with aging
B Sarg et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Lipofuscin: Mechanisms of age-related accumulation and influence on cell function
UT Brunk et al.
FREE RADICAL BIOLOGY AND MEDICINE (2002)
Cytomegalovirus seropositivity drives the CD8 T cell repertoire toward greater clonality in healthy elderly individuals
N Khan et al.
JOURNAL OF IMMUNOLOGY (2002)
The threshold for polyglutamine-expansion protein aggregation and cellular toxicity is dynamic and influenced by aging in Caenorhabditis elegans
JF Morley et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Calorie restriction in biosphere 2: Alterations in physiologic, hematologic, hormonal, and biochemical parameters in humans restricted for a 2-year period
RL Walford et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2002)
Lack of antibody production following immunization in old age:: Association with CD8+CD28- T cell clonal expansions and an imbalance in the production of Th1 and Th2 cytokines
M Saurwein-Teissl et al.
JOURNAL OF IMMUNOLOGY (2002)
Regulation of lifespan by histone deacetylase
KT Chang et al.
AGEING RESEARCH REVIEWS (2002)
Reactive oxygen species differentially affect T cell receptor-signaling pathways
S Cemerski et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Increased thymic mass and circulating naive CD4 T cells in HIV-1-infected adults treated with growth hormone
LA Napolitano et al.
AIDS (2002)
Premature aging in mice deficient in DNA repair and transcription
J de Boer et al.
SCIENCE (2002)
Requirement for a hsp90 chaperone-dependent MEK1/2-ERK pathway for B cell antigen receptor-induced cyclin D2 expression in mature B lymphocytes
MJ Piatelli et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Age-associated loss of bone marrow hematopoietic cells is reversed by GH and accompanies thymic reconstitution
RA French et al.
ENDOCRINOLOGY (2002)
Calcium and oxidative stress: from cell signaling to cell death
G Ermak et al.
MOLECULAR IMMUNOLOGY (2002)
Ubiquitin-proteasome pathway is compromised in CD45RO(+) and CD45RA(+) T lymphocyte subsets during aging
U Ponnappan
EXPERIMENTAL GERONTOLOGY (2002)
V alpha 24(+) NKT cells are decreased in elderly humans
O DelaRosa et al.
EXPERIMENTAL GERONTOLOGY (2002)
T cell receptor excision circle assessment of thymopoiesis in aging mice
GD Semposski et al.
MOLECULAR IMMUNOLOGY (2002)
Differential maintenance and de novo methylating activity by three DNA methyltransferases in aging and immortalized fibroblasts
N Lopatina et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2002)
Tumour necrosis factor-alpha-induced migration of human Langerhans cells: the influence of ageing
M Bhushan et al.
BRITISH JOURNAL OF DERMATOLOGY (2002)
Effect of redox balance alterations on cellular localization of LAT and downstream T-cell receptor signaling pathways
SI Gringhuis et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Reduced levels of oxidized and glycoxidized proteins in human fibroblasts exposed to repeated mild heat shock during serial passaging in vitro
P Verbeke et al.
FREE RADICAL BIOLOGY AND MEDICINE (2001)
Age-related alterations in the inflammatory response to dermal injury
ME Swift et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2001)
Vitamin E-enhanced IL-2 production in old mice: Naive but not memory T cells show increased cell division cycling and IL-2-producing capacity
O Adolfsson et al.
JOURNAL OF IMMUNOLOGY (2001)
Neutrophil ageing and immunesenescence
JM Lord et al.
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Age-related changes in membrane lipid composition, fluidity and respiratory burst in rat peritoneal neutrophils
E Alvarez et al.
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A potential role for protein tyrosine kinase p56lck in rheumatoid arthritis synovial fluid T lymphocyte hyporesponsiveness
P Romagnoli et al.
INTERNATIONAL IMMUNOLOGY (2001)
IFN-γ-dependent transcription of MHC class IIIA is impaired in macrophages from aged mice
C Herrero et al.
JOURNAL OF CLINICAL INVESTIGATION (2001)
IL-7 and not stem cell Factor Reverses both the increase in apoptosis and the decline in thymopoiesis seen in aged mice
D Andrew et al.
JOURNAL OF IMMUNOLOGY (2001)
Oxidants, oxidative stress and the biology of ageing
T Finkel et al.
NATURE (2000)
Age-related decline in chaperone-mediated autophagy
AM Cuervo et al.
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Lipid rafts and signal transduction
K Simons et al.
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Functional heterogeneity and high frequencies of cytomegalovirus-specific CD8+ T lymphocytes in healthy seropositive donors
GMA Gillespie et al.
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Lineage-specific telomere shortening and unaltered capacity for telomerase expression in human T and B lymphocytes with age
NH Son et al.
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Altered composition of the immunological synapse in an anergic, age-dependent memory T cell subset
MD Eisenbraun et al.
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N-t-butyl hydroxylamine, a hydrolysis product of α-phenyl-N-t-butyl nitrone, is more potent in delaying senescence in human lung fibroblasts
H Atamna et al.
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Recent advances towards understanding redox mechanisms in the activation of nuclear factor κB
YMW Janssen-Heininger et al.
FREE RADICAL BIOLOGY AND MEDICINE (2000)
Unimpaired dendritic cells call be derived from monocytes in old age and can mobilize residual function in senescent T cells
TL Lung et al.
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Leukemia inhibitory factor, oncostatin M, IL-6, and stem cell factor mRNA expression in human thymus increases with age and is associated with thymic atrophy
GD Sempowski et al.
JOURNAL OF IMMUNOLOGY (2000)
Displacement of linker for activation of T cells from the plasma membrane due to redox balance alterations results in hyporesponsiveness of synovial fluid T lymphocytes in rheumatoid arthritis
SI Gringhuis et al.
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Functional alteration of granulocytes, NK cells, and natural killer T cells in centenarians
C Miyaji et al.
HUMAN IMMUNOLOGY (2000)
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