Journal
ACTA NEUROLOGICA SCANDINAVICA
Volume 112, Issue 4, Pages 207-213Publisher
WILEY
DOI: 10.1111/j.1600-0404.2005.00414.x
Keywords
multiple sclerosis; neurosarcoidosis; neurolupus; Sjogren's syndrome; neuro-Behcet; cerebrospinal fluid
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A number of neurological syndromes may be evoked by involvement of the nervous system due to systemic diseases such as lupus erythematodes, sarcoidosis, Behcet's disease and Sjogren's syndrome (SS) and may be confounded with another chronic inflammatory disease which is restricted to the central nervous system, e.g. multiple sclerosis (MS). Because of different treatment strategies, it is important to distinguish between these different autoimmune diseases. Results - Neither clinical signs nor additional analyses such as serological findings or cerebrospinal fluid (CSF) analysis are able to differentiate between the diseases with certainty Nevertheless, taking all findings together, diagnosis may be possible. Conclusion - Here we compare typical clinical and CSF findings in MS, neurosarcoidosis, neurolupus, neuro-Beh et and nervous system involving SS with special emphasis on those findings allowing differentiation of the respective diseases by reviewing the literature.
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