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SCIENCE (2003)
Haem oxygenase 1 gene induction by glucose deprivation is mediated by reactive oxygen species via the mitochondrial electron-transport chain
SH Chang et al.
BIOCHEMICAL JOURNAL (2003)
Functional consequences of endothelial nitric oxide synthase uncoupling in congestive cardiac failure
LJ Dixon et al.
CIRCULATION (2003)
Diabetes and mitochondrial oxidative stress:: A study using heart mitochondria from the diabetic Goto-Kakizaki rat
DL Santos et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2003)
Monocyte NADPH oxidase subunit p22phox and inducible hemeoxygenase-1 gene expressions are increased in type II diabetic patients:: Relationship with oxidative stress
A Avogaro et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2003)
Thioredoxin-dependent redox regulation of the antioxidant responsive element (ARE) in electrophile response
YC Kim et al.
ONCOGENE (2003)
Mitochondrial dysfunction and death in motor neurons exposed to the glutathione-depleting agent ethacrynic acid
M Rizzardini et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2003)
Laminar flow induction of antioxidant response element-mediated genes in endothelial cells - A novel anti-inflammatory mechanism
XL Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation
N Wakabayashi et al.
NATURE GENETICS (2003)
Regulation of amino acid and glucose transporters in endothelial and smooth muscle cells
GE Mann et al.
PHYSIOLOGICAL REVIEWS (2003)
Novel role of gp91phox-containing NAD(P)H oxidase in vascular endothelial growth factor-induced signaling and angiogenesis
M Ushio-Fukai et al.
CIRCULATION RESEARCH (2002)
Electrophile response element-mediated induction of the cystine/glutamate exchange transporter gene expression
H Sasaki et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Redox analysis of human plasma allows separation of pro-oxidant events of aging from decline in antioxidant defenses
DP Jones et al.
FREE RADICAL BIOLOGY AND MEDICINE (2002)
Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants
AT Dinkova-Kostova et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2, Gstm3 and Gstm4 genes in the livers of male and female mice
SA Chanas et al.
BIOCHEMICAL JOURNAL (2002)
Microsatellite polymorphism in promoter of heme oxygenase-1 gene is associated with susceptibility to coronary artery disease in type 2 diabetic patients
YH Chen et al.
HUMAN GENETICS (2002)
Diabetes and atherosclerosis - Epidemiology, pathophysiology, and management
JA Beckman et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2002)
Mechanisms of increased vascular superoxide production in human diabetes mellitus Role of NAD(P)H oxidase and endothelial nitric oxide synthase
TJ Guzik et al.
CIRCULATION (2002)
Vascular NADH oxidase is involved in impaired endothelium-dependent vasodilation in OLETF rats, a model of type 2 diabetes
YK Kim et al.
DIABETES (2002)
Biochemistry and molecular cell biology of diabetic complications
M Brownlee
NATURE (2001)
Mitochondrial function in normal and diabetic β-cells
P Maechler et al.
NATURE (2001)
Global and societal implications of the diabetes epidemic
P Zimmet et al.
NATURE (2001)
Diabetes-associated sustained activation of the transcription factor nuclear factor-κB
A Bierhaus et al.
DIABETES (2001)
Improved arterial compliance by a novel advanced glycation end-product crosslink breaker
DA Kass et al.
CIRCULATION (2001)
Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, β cell dysfunction, and type 2 diabetes
CY Zhang et al.
CELL (2001)
Activation of NADPH oxidase by AGE links oxidant stress to altered gene expression via RAGE
MP Wautier et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2001)
An important function of Nrf2 in combating oxidative stress: Detoxification of acetaminophen
KM Chan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Impaired expression of glutathione synthetic enzyme genes in mice with targeted deletion of the Nrf2 basic-leucine zipper protein
JY Chan et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION (2000)
NAD(P)H:quinone oxidoreductase 1 (NQO1):: chemoprotection, bioactivation, gene regulation and genetic polymorphisms
D Ross et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2000)
Oxidants, oxidative stress and the biology of ageing
T Finkel et al.
NATURE (2000)
Regulation of the antioxidant response element by protein kinase C-mediated phosphorylation of NF-E2-related factor 2
HC Huang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C-dependent activation of NAD(P)H oxidase in cultured vascular cells
T Inoguchi et al.
DIABETES (2000)
The NADPH oxidase of endothelial cells
BM Babior
IUBMB LIFE (2000)
Free radicals mediate endothelial dysfunction of coronary arterioles in diabetes
RF Ammar et al.
CARDIOVASCULAR RESEARCH (2000)
Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages
T Ishii et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage
T Nishikawa et al.
NATURE (2000)
The Nrf2 transcription factor contributes both to the basal expression of glutathione S-transferases in mouse liver and to their induction by the chemopreventive synthetic antioxidants, butylated hydroxyanisole and ethoxyquin
JD Hayes et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2000)
The missing link: A single unifying mechanism for diabetic complications
T Nishikawa et al.
KIDNEY INTERNATIONAL (2000)