Journal
ANTIOXIDANTS & REDOX SIGNALING
Volume 15, Issue 5, Pages 1427-1432Publisher
MARY ANN LIEBERT INC
DOI: 10.1089/ars.2010.3741
Keywords
-
Funding
- National Institutes of Health [HL36049 MERIT, HL64388, HL62250]
- American Heart Association [AHA0315286U]
Ask authors/readers for more resources
Endothelial phenotype heterogeneity plays an important role in the susceptibility of arteries to atherosclerosis. Regions of blood flow disturbance correlate with the development of disease. Here, we briefly outline the association of endoplasmic reticulum stress with endothelium in regions of athero-susceptibility in vivo. It is an important example of susceptible cell phenotype that is likely linked to proinflammatory and oxidative stress pathways. The endothelium in such regions is chronically exposed to complex hemodynamic shear stresses that may be considered as a risk factor for atherosclerosis via these mechanisms. Antioxid. Redox Signal. 15, 1427-1432.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available