Journal
JOURNAL OF SEPARATION SCIENCE
Volume 28, Issue 15, Pages 1855-1875Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/jssc.200500186
Keywords
beads; characterization; chromatography; dispersion; HPLC; methacrylates; monodisperse; packings; particles; polymer; polymerization; separation modes; suspension
Categories
Funding
- NIGMS NIH HHS [GM-44885] Funding Source: Medline
Ask authors/readers for more resources
This review summarizes the preparation and application of chromatographic separation media based on methacrylate monomers with a major focus on highly crosslinked macroporous beads prepared from 2-hydroxyethyl methacrylate and glycidyl methacrylate, respectively. The effects of process variables such as composition of the polymerization mixture that includes monomers, porogenic solvents, and free radical initiator, suspension stabilizer, reaction temperature, and stirring are detailed for both classical and templated suspension polymerization. In addition, specific features of the preparation of monodisperse beads are also discussed. The performance of methacrylate-based separation media is demonstrated on numerous separations in a variety of chromatographic modes.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available