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The role of oxidative stress in diabetic vascular and neural disease
MA Yorek
FREE RADICAL RESEARCH (2003)
New insights on oxidative stress and diabetic complications may lead to a causal antioxidant therapy
A Ceriello
DIABETES CARE (2003)
Oxidative stress and insulin requirements in patients with recent-onset type 1 diabetes
RD Hoeldtke et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2003)
Proteome analysis reveals phosphorylation of ATP synthase β-subunit in human skeletal muscle and proteins with potential roles in type 2 diabetes
K Hojlund et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Role of protein kinase C on the expression of platelet-derived growth factor and endothelin-1 in the retina of diabetic rats and cultured retinal capillary pericytes
T Yokota et al.
DIABETES (2003)
Ascorbic acid blunts oxidant stress due to menadione in endothelial cells
JM May et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2003)
Mitochondrial biogenesis in mammals: The role of endogenous nitric oxide
E Nisoli et al.
SCIENCE (2003)
Increased uncoupling protein 3 content does not affect mitochondrial function in human skeletal muscle in vivo
MKC Hesselink et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
NAD(P)H, a primary target of 1O2 in mitochondria of intact cells
F Petrat et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Preventing superoxide formation in epineurial arterioles of the sciatic nerve from diabetic rats restores endothelium-dependent vasodilation
LJ Coppey et al.
FREE RADICAL RESEARCH (2003)
Superoxide-mediated activation of uncoupling protein 2 causes pancreatic beta cell dysfunction
S Krauss et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
Transcellular transport of a highly polar 3+net charge opioid tetrapeptide
KS Zhao et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2003)
Comparison of [Dmt(1)]DALDA and DAMGO in binding and G protein activation at mu, delta, and kappa opioid receptors
GM Zhao et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2003)
Minireview: Malonyl CoA, AMP-activated protein kinase, and adiposity
NB Ruderman et al.
ENDOCRINOLOGY (2003)
Membrane-permeable radical scavengers (tempol) for shock, ischemia-reperfusion injury, and inflammation
C Thiemermann
CRITICAL CARE MEDICINE (2003)
Diabetes-induced mitochondrial dysfunction in the retina
RA Kowluru et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2003)
Oxidative stress in diabetes
L Piconi et al.
CLINICAL CHEMISTRY AND LABORATORY MEDICINE (2003)
Superoxide activates mitochondrial uncoupling protein 2 from the matrix side - Studies using targeted antioxidants
KS Echtay et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Topology of superoxide production from different sites in the mitochondrial electron transport chain
J St-Pierre et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
A central role for JNK in obesity and insulin resistance
J Hirosumi et al.
NATURE (2002)
Increased mitochondrial mass in mitochondrial myopathy mice
A Wredenberg et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Effect of treatment of diabetic rats with dehydroepiandrosterone on vascular and neural function
MA Yorek et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2002)
Uncoupling protein 2 knockout mice have enhanced insulin secretory capacity after a high-fat diet
JW Joseph et al.
DIABETES (2002)
Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes
DE Kelley et al.
DIABETES (2002)
Effects of trientine, a metal chelator, on defective endothelium-dependent relaxation in the mesenteric vasculature of diabetic rats
ME Inkster et al.
FREE RADICAL RESEARCH (2002)
Nonalcoholic fatty liver disease: Pathogenesis and the role of antioxidants
K Mehta et al.
NUTRITION REVIEWS (2002)
Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres
J Lin et al.
NATURE (2002)
Exercise effects of muscle insulin signaling and action - Invited review: Effects of acute exercise and exercise training on insulin resistance
EJ Henriksen
JOURNAL OF APPLIED PHYSIOLOGY (2002)
No evidence for a basal, retinoic, or superoxide-induced uncoupling activity of the uncoupling protein 2 present in spleen or lung mitochondria
E Couplan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Oxidative DNA damage and tubulointerstitial injury in diabetic nephropathy
M Kanauchi et al.
NEPHRON (2002)
Vitamin C matters: increased oxidative stress in cultured human aortic endothelial cells without supplemental ascorbic acid
AR Smith et al.
FASEB JOURNAL (2002)
Catalase-dependent measurement of H2O2 in intact mitochondria
X Li et al.
MITOCHONDRION (2002)
Effect of α-lipoic acid on lipid peroxidation and anti-oxidant enzyme activities in diabetic rats
Y Dinçer et al.
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2002)
Diabetes impairs the enzymatic disposal of 4-hydroxynonenal in rat liver
N Traverso et al.
FREE RADICAL BIOLOGY AND MEDICINE (2002)
UCP2-dependent proton leak in isolated mammalian mitochondria
BD Fink et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
WC Knowler et al.
NEW ENGLAND JOURNAL OF MEDICINE (2002)
Effects of the superoxide dismutase-mimetic compound tempol on endothelial dysfunction in streptozotocin-induced diabetic rats
T Nassar et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2002)
Early increase of oxidative stress and reduced antioxidant defenses in patients with uncomplicated type 1 diabetes: a case for gender difference
G Marra et al.
DIABETES CARE (2002)
The basal proton conductance of skeletal muscle mitochondria from transgenic mice overexpressing or lacking uncoupling protein-3
S Cadenas et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Superoxide activates mitochondrial uncoupling proteins
KS Echtay et al.
NATURE (2002)
Insulin resistance and vascular function
AD Baron
JOURNAL OF DIABETES AND ITS COMPLICATIONS (2002)
How mitochondrial damage affects cell function
AM James et al.
JOURNAL OF BIOMEDICAL SCIENCE (2002)
Δψm-dependent and -independent production of reactive oxygen species by rat brain mitochondria
TV Votyakova et al.
JOURNAL OF NEUROCHEMISTRY (2001)
Uncoupling protein 3 content is decreased in skeletal muscle of patients with type 2 diabetes
P Schrauwen et al.
DIABETES (2001)
Chronic activation of AMP kinase results in NRF-1 activation and mitochondrial biogenesis
R Bergeron et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2001)
The regulation of AMP-activated protein kinase by H2O2.
SL Choi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
Release of Ca2+ from mitochondria via the saturable mechanisms and the permeability transition
DR Pfeiffer et al.
IUBMB LIFE (2001)
The mitochondrial uncoupling protein UCP1: A gated pore
I Arechaga et al.
IUBMB LIFE (2001)
Uptake of calcium by mitochondria: Transport and possible function
TE Gunter et al.
IUBMB LIFE (2001)
Effect of M40403 treatment of diabetic rats on endoneurial blood flow, motor nerve conduction velocity and vascular function of epineurial arterioles of the sciatic nerve
LJ Coppey et al.
BRITISH JOURNAL OF PHARMACOLOGY (2001)
Effects of the hydroxyl radical scavenger, dimethylthiourea, on peripheral nerve tissue perfusion, conduction velocity and nociception in experimental diabetes
NE Cameron et al.
DIABETOLOGIA (2001)
Nitric oxide, mitochondria, and cell death
GC Brown et al.
IUBMB LIFE (2001)
Apoptosis and mitochondrial damage in INS-1 cells treated with alloxan
K Sakurai et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2001)
Low acute insulin secretory responses in adult offspring of people with early onset type 2 diabetes
JF Gautier et al.
DIABETES (2001)
Effect of antioxidant treatment of streptozotocin-induced diabetic rats on endoneurial blood flow, motor nerve conduction velocity, and vascular reactivity of epineurial arterioles of the sciatic nerve
LJ Coppey et al.
DIABETES (2001)
Leptin induces mitochondrial superoxide production and monocyte chemoattractant protein-1 expression in aortic endothelial cells by increasing fatty acid oxidation via protein kinase A
SI Yamagishi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Effect of α-lipoic acid on vascular responses and nociception in diabetic rats
NE Cameron et al.
FREE RADICAL BIOLOGY AND MEDICINE (2001)
Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, β cell dysfunction, and type 2 diabetes
CY Zhang et al.
CELL (2001)
In vivo effects of uncoupling protein-3 gene disruption on mitochondrial energy metabolism
GW Cline et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Effects of an extracellular metal chelator on neurovascular function in diabetic rats
NE Cameron et al.
DIABETOLOGIA (2001)
Skeletal muscle lipid content and oxidative enzyme activity in relation to muscle fiber type in type 2 diabetes and obesity
J He et al.
DIABETES (2001)
Continuous fatty acid oxidation and reduced fat storage in mice lacking acetyl-CoA carboxylase 2
L Abu-Elheiga et al.
SCIENCE (2001)
Mitochondrial proton leak and the uncoupling protein 1 homologues
JA Stuart et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2001)
Selective targeting of a redox-active ubiquinone to mitochondria within cells - Antioxidant and antiapoptotic properties
GF Kelso et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Uncoupling proteins 2 and 3 are highly active H+ transporters and highly nucleotide sensitive when activated by coenzyme Q (ubiquinone)
KS Echtay et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Effects of adenoviral overexpression of uncoupling protein-2 and-3 on mitochondrial respiration in insulinoma cells
Y Hong et al.
ENDOCRINOLOGY (2001)
Diabetes-induced changes in retinal NAD-redox status - Pharmacological modulation and implications for pathogenesis of diabetic retinopathy
IG Obrosova et al.
PHARMACOLOGY (2001)
Mitochondrial calcium transport: mechanisms and functions
TE Gunter et al.
CELL CALCIUM (2000)
Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation
XL Du et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Synthesis and in vitro opioid activity profiles of DALDA analogues
PW Schiller et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2000)
Mitochondria, oxygen free radicals, disease and ageing
S Raha et al.
TRENDS IN BIOCHEMICAL SCIENCES (2000)
Impact of endotoxin on UCP homolog mRNA abundance, thermoregulation, and mitochondrial proton leak kinetics
XX Yu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2000)
Oxidative stress and cardiovascular complications in diabetes: isoprostanes as new markers on an old paradigm
A Mezzetti et al.
CARDIOVASCULAR RESEARCH (2000)
Signaling pathways in insulin action: molecular targets of insulin resistance
JE Pessin et al.
JOURNAL OF CLINICAL INVESTIGATION (2000)
Endothelial dysfunction in diabetes
AS De Vriese et al.
BRITISH JOURNAL OF PHARMACOLOGY (2000)
Mitochondrial adaptations to obesity-related oxidant stress
SQ Yang et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2000)
Activation of AMP-activated protein kinase increases mitochondrial enzymes in skeletal muscle
WW Winder et al.
JOURNAL OF APPLIED PHYSIOLOGY (2000)
Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage
T Nishikawa et al.
NATURE (2000)
Uncoupling proteins 2 and 3 - Potential regulators of mitochondrial energy metabolism
O Boss et al.
DIABETES (2000)
Vitamin E supplementation and cardiovascular events in high-risk patients
S Yusuf et al.
NEW ENGLAND JOURNAL OF MEDICINE (2000)
The missing link: A single unifying mechanism for diabetic complications
T Nishikawa et al.
KIDNEY INTERNATIONAL (2000)
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