Journal
JOURNAL OF BACTERIOLOGY
Volume 187, Issue 20, Pages 7155-7160Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JB.187.20.7155-7160.2005
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The first genetic, in vivo, and in vitro evidences that YrxA is the regulator of NAD de novo biosynthesis in Bacillus subtilis are hereby reported. The protein is essential to the transcription repression of the divergent operons nadBCA and nifS-yrxA in the presence of nicotinic acid and binds to their shared operator-promoter region.
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