Journal
ACTA RADIOLOGICA
Volume 46, Issue 6, Pages 618-620Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/02841850510021517
Keywords
brain; magnetic resonance imaging; globus pallidus lesions; tyrosinemia
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A 3.5-year-old girl with tyrosinemia is reported. A computed tomography scan of the abdomen revealed multiple hepatic nodules. Brain magnetic resonance imaging revealed bilateral high-signal changes confined to the globus pallidus on T2-weighted images. Globus pallidus lesions likely represented neuropathologic changes such as astocytosis, delayed myelination, and status spongiosus (myelin splitting and vacuolation).
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