Journal
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 59, Issue 2, Pages 1365-1369Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.04417-14
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Funding
- Ministry of Science and Technology [2012ZX09103201-039]
- National Natural Science Foundation of China [81471925]
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The in vitro activity of chloroquine and the interactions of chloroquine combined with fluconazole against 37 Candida isolates were tested using the broth microdilution, disk diffusion, and Etest susceptibility tests. Synergistic effect was detected with 6 of 9 fluconazole-resistant Candida albicans isolates, with Candida krusei ATCC 6258, and with all 12 fluconazole-resistant Candida tropicalis isolates.
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