4.7 Article

OXA-48 Carbapenemase-Producing Salmonella enterica Serovar Kentucky Isolate of Sequence Type 198 in a Patient Transferred from Libya to Switzerland

Journal

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 58, Issue 4, Pages 2446-2449

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.02417-13

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Funding

  1. Institute of Infectious Diseases of Bern (IFIK)
  2. Swiss Veterinary Federal Office (BVET) [1.12.06]
  3. BVET
  4. IFIK

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Here, we report a case of OXA-48-producing Salmonella enterica serovar Kentucky of sequence type 198 (ST198) from perianal screening cultures of a patient transferred from Libya to Switzerland. The bla(OXA-48) gene was carried by Tn1999.2 and located on an similar to 60-kb IncL/M plasmid. This Salmonella strain also possessed the bla(VEB-8), aac(6)-Ib, tet(A), sul1, and mphA resistance genes and substitutions in GyrA (Ser83Phe and Asp87Asn) and ParC (Ser80Ile). This finding emphasizes that prompt screening strategies are essential to prevent the dissemination of carbapenemase producers imported from countries where they are endemic.

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