4.7 Article

Association of Class 1 and 2 Integrons with Multidrug-Resistant Acinetobacter baumannii International Clones and Acinetobacter nosocomialis Isolates

Journal

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 59, Issue 1, Pages 698-701

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.02415-14

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Funding

  1. Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq)
  2. Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES)
  3. Comissao Fullbright-Brasil
  4. Fundacao de Amparo a Pesquisa do Estado do Rio de Janeiro (FAPERJ)
  5. Agencia Nacional de Vigilancia Sanitaria (ANVISA) of Brazil
  6. Fogarty International Program in Global Infectious Diseases of the National Institutes of Health [TW006563]

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The Acinetobacter baumannii clonal complex 113/79 (CC113/79) and class 2 integrons predominate in Latin America; a relationship between these characteristics was explored. The presence of integrases was determined in successive hospital Acinetobacter isolates (163 A. baumannii isolates and 72 Acinetobacter nosocomialis isolates). Most isolates had integrons, but class 1 and 2 integrons were present significantly more often in CC109/1 and CC113/79, respectively. The high prevalence of CC113/79 in Latin America may account for the predominance of class 2 integrons.

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