4.7 Article

Comparison between the EUCAST Procedure and the Etest for Determination of the Susceptibility of Candida Species Isolates to Micafungin

Journal

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 57, Issue 11, Pages 5767-5770

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.01032-13

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Funding

  1. Fondo de Investigacion Sanitaria (FIS) [PI11/00167]
  2. Astellas Pharma
  3. FIS [CD09/00230, MS09/00055, FI12/00265, CD11/00110]

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We compared the ability of the EUCAST EDef 7.2 and the Etest to detect the susceptibility to micafungin of 160 Candida and non-Candida clinical isolates. Agreement was higher when Etest MICs were obtained after 24 h of incubation; essential agreement was 90%, and categorical agreement was >90%. False susceptibility was seen only for Candida krusei (10%), and false resistance was observed in 6% of the isolates, ranging from 2.6% (C. glabrata) to 13% (C. albicans).

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