Journal
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 57, Issue 6, Pages 2834-2837Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.02542-12
Keywords
-
Categories
Funding
- NIH Fogarty International Center [TW00018]
- National Institutes of Allergy and Infectious Diseases [AI098627]
- Milstein Program for Chemical Biology of Infectious Disease
- William Randolph Hearst Foundation
Ask authors/readers for more resources
Nitazoxanide (NTZ) has bactericidal activity against the H37Rv laboratory strain of Mycobacterium tuberculosis with a MIC of 16 mu g/ml. However, its efficacy against clinical isolates of M. tuberculosis has not been determined. We found that NTZ's MIC against 50 clinical isolates ranged from 12 to 28 mu g/ml with a median of 16 mu g/ml and was unaffected by resistance to first-or second-line antituberculosis drugs or a diversity of spoligotypes.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
