4.4 Article

An efficient and convenient KF/Al2O3 mediated synthesis of nitriles from aldehydes

Journal

TETRAHEDRON LETTERS
Volume 46, Issue 40, Pages 6923-6925

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2005.08.007

Keywords

aldehydes; nitrites; KF/Al2O3; heterogeneous reaction; hydroxylamine hydrochloride

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KF/Al2O3 brings about a facile one-pot and economical conversion of various aryl and alkyl aldehydes into the corresponding nitriles in high yields by reaction with hydroxylamine hydrochloride. (c) 2005 Elsevier Ltd. All rights reserved.

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