Journal
CHEMISTRY-A EUROPEAN JOURNAL
Volume 11, Issue 20, Pages 6006-6013Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.200500605
Keywords
core-shell structures; drug carriers; fluorescence; magnetic properties; thermoresponsive
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Novel functional microspheres with multistimuli-responsive properties have been prepared and characterized. The as-prepared microspheres respond to an external magnetic field, environmental temperature, and ultraviolet radiation. The in vitro drug-loading efficiency and drug-released behavior of these microspheres demonstrated that they could be used as drug carriers for drug controlled release. The results of in vivo distribution investigations of these microspheres showed that they exhibit a high magnetic-targeting effect, which holds promise for applications in various fields such as magnetic drug targeting and tissue labeling, among others.
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