Journal
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 57, Issue 2, Pages 1073-1076Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.01886-12
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Funding
- FEMS Advanced Fellowship
- Czech Science Foundation [P502/10/P083]
- CEITEC [CZ.1.05/1.1.00/02.0068]
- MIUR
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The entire plasmid content of a multidrug-resistant, CTX-M-15-producing Klebsiella pneumoniae ST416 clone was investigated. Two FII kappa plasmids, pKDO1 (127 kb) and pKPN-CZ (207 kb), were identified and found to carry a formidable set of genes conferring resistance to toxic compounds, metals, and antimicrobial drugs and exhibiting novel features putatively associated with adaptation and fitness of the bacterium in the human host.
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