Journal
VETERINARY PARASITOLOGY
Volume 133, Issue 1, Pages 7-11Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.vetpar.2005.04.034
Keywords
sleeping sickness; Trypanosoma brucei gambiense; animal reservoir; pig; self cure; tsetse control
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The existence of a pig reservoir for human African trypanosomosis (HAT) due to Trypanosoma brucei gambiense complicates the fight against this disease. This study, reports results obtained from pigs, which were inoculated with the blood of a person, suffering from HAT in Cameroon. The pigs were reared and kept in the shelter from all contact with Glossina, and monitored for 188 days. The seroconversion was checked by agglutination assays for trypanosomosis (CATT 1.3 and LATEX/Tb.gambiense). The parasitemia was measured by quantitative buffy coat method (QBC) and by polymerase chain reaction method (PCR). In addition, growth was recorded as well as blood counting and blood formulas. The results showed that the pigs were trypanotolerant and cure themselves in less than 6 months. It is concluded that sterilisation of this reservoir could be achieved by tsetse-control measures in 1 year. It confirms the strategy to complement screening and treatment of HAT with tsetse fly control measures. (c) 2005 Elsevier B.V. All rights reserved.
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