Journal
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 56, Issue 11, Pages 6029-6032Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.01189-12
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Funding
- Australian National Health and Medical Research Council [512396]
- Life Science Research Award
- New South Wales Office of Science and Medical Research
- NHMRC Practitioner Fellowship [1002976]
- National Institute of Allergy and Infectious Diseases
- National Institutes of Health, Department of Health and Human Services (NIAD) [HHSN266200400042C]
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Complete sequencing of pEl1573, a representative IncL/M plasmid carrying bla(IMP-4) from Sydney, Australia, revealed an similar to 60-kb backbone almost identical to those of IncL/M plasmids pCTX-M3, from Poland, and pCTX-M360, from China, and less closely related to pNDM-HK, pOXA-48a, and pEL60, suggesting different lineages. The similar to 28-kb Tn2-derived multiresistance region in pEl1573 is inserted in the same location as those in pCTX-M3 and pNDM-HK and shares some of the same components but has undergone rearrangements.
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